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3/6/2026 8:56:31 AM | Browse: 52 | Download: 97
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Received |
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2025-10-25 09:04 |
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Peer-Review Started |
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2025-10-25 09:04 |
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First Decision by Editorial Office Director |
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2025-10-30 08:54 |
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2025-10-30 08:54 |
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Revised |
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2025-11-06 16:58 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-04 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-04 06:04 |
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Articles in Press |
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2025-12-04 06:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-31 13:14 |
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Publish the Manuscript Online |
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2026-03-06 08:56 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Role of plasma D-dimer levels as diagnostic and prognostic marker in neonatal sepsis: An insightful support
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alessandro Boscarelli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Alessandro Boscarelli, MD, Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, via dell'Istria, 65/1, Trieste 34137, Italy. alessandro.boscarelli@burlo.trieste.it |
| Key Words |
D-dimer; Neonatal sepsis; Diagnosis; Prognosis; Assessment tool |
| Core Tip |
Despite advances in neonatal care, sepsis remains a serious health problem with significant morbidity and mortality. Clinical diagnosis at presentation is often challenging due to nonspecific signs and symptoms. Laboratory biomarkers, blood cultures, and other diagnostic/prognostic tools are not considered reliable for routine clinical use. Basiouny et al conducted a two-center prospective case-control study investigating the diagnostic and prognostic utility of D-dimer and heparin-binding protein in neonatal sepsis. While future multicenter studies with larger patient populations are required, these findings indicate the utility of D-dimer inclusion in sepsis diagnostic models. |
| Publish Date |
2026-03-06 08:56 |
| Citation |
Boscarelli A. Role of plasma D-dimer levels as diagnostic and prognostic marker in neonatal sepsis: An insightful support. World J Clin Pediatr 2026; 15(1): 115780 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i1/115780.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i1.115780 |
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