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3/6/2026 8:56:31 AM | Browse: 3 | Download: 12
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 115780
Country Italy
Received
2025-10-25 09:04
Peer-Review Started
2025-10-25 09:04
First Decision by Editorial Office Director
2025-10-30 08:54
Return for Revision
2025-10-30 08:54
Revised
2025-11-06 16:58
Publication Fee Transferred
Second Decision by Editor
2025-12-04 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-04 06:04
Articles in Press
2025-12-04 06:04
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-31 13:14
Publish the Manuscript Online
2026-03-06 08:56
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Letter to the Editor
Article Title Role of plasma D-dimer levels as diagnostic and prognostic marker in neonatal sepsis: An insightful support
Manuscript Source Invited Manuscript
All Author List Alessandro Boscarelli
ORCID
Author(s) ORCID Number
Alessandro Boscarelli http://orcid.org/0000-0003-1934-1764
Funding Agency and Grant Number
Corresponding Author Alessandro Boscarelli, MD, Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, via dell'Istria, 65/1, Trieste 34137, Italy. alessandro.boscarelli@burlo.trieste.it
Key Words D-dimer; Neonatal sepsis; Diagnosis; Prognosis; Assessment tool
Core Tip Despite advances in neonatal care, sepsis remains a serious health problem with significant morbidity and mortality. Clinical diagnosis at presentation is often challenging due to nonspecific signs and symptoms. Laboratory biomarkers, blood cultures, and other diagnostic/prognostic tools are not considered reliable for routine clinical use. Basiouny et al conducted a two-center prospective case-control study investigating the diagnostic and prognostic utility of D-dimer and heparin-binding protein in neonatal sepsis. While future multicenter studies with larger patient populations are required, these findings indicate the utility of D-dimer inclusion in sepsis diagnostic models.
Publish Date 2026-03-06 08:56
Citation

Boscarelli A. Role of plasma D-dimer levels as diagnostic and prognostic marker in neonatal sepsis: An insightful support. World J Clin Pediatr 2026; 15(1): 115780

URL https://www.wjgnet.com/2219-2808/full/v15/i1/115780.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i1.115780
Full Article (PDF) WJCP-15-115780-with-cover.pdf
Manuscript File 115780_Auto_Edited_082227.docx
Answering Reviewers 115780-answering-reviewers.pdf
Audio Core Tip 115780-audio.mp3
Conflict-of-Interest Disclosure Form 115780-conflict-of-interest-statement.pdf
Copyright License Agreement 115780-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115780-non-native-speakers.pdf
Peer-review Report 115780-peer-reviews.pdf
Scientific Misconduct Check 115780-scientific-misconduct-check.png
Scientific Editor Work List 115780-scientific-editor-work-list.pdf
CrossCheck Report 115780-crosscheck-report.pdf