BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/27/2026 8:35:10 AM | Browse: 2 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115785
Country Egypt
Received
2025-10-25 09:01
Peer-Review Started
2025-10-25 09:01
First Decision by Editorial Office Director
2025-11-24 12:55
Return for Revision
2025-11-24 12:55
Revised
2025-12-02 22:08
Publication Fee Transferred
Second Decision by Editor
2026-01-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-04 07:25
Articles in Press
2026-01-04 07:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-10 08:14
Publish the Manuscript Online
2026-02-27 08:35
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Lessons from extended induction and practical evidence for improving tofacitinib therapy in ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Yasser Fouad and Ahmed S Aboelela
ORCID
Author(s) ORCID Number
Yasser Fouad http://orcid.org/0000-0001-7989-5318
Ahmed S Aboelela http://orcid.org/0000-0006-1362-5183
Funding Agency and Grant Number
Corresponding Author Yasser Fouad, Department of Gastroenterology and Endemic Medicine, Faculty of Medicine, Minia University, El Horryia Street, Minia 19111, Egypt. yasserfouad10@yahoo.com
Key Words Tofacitinib; Ulcerative colitis; Induction therapy; Maintenance therapy; Janus kinase
Core Tip Partial or delayed responders with ulcerative colitis can be saved by extending tofacitinib induction from 8 weeks to 16 weeks without raising safety concerns. Evidence from the real world shows that this approach, especially in patients with biologic experience, results in higher remission rates and long-lasting drug persistence. Instead of a strict 8-week limit, a structured, response-guided algorithm enables clinicians to address modifiable risk factors like smoking, maximize long-term outcomes, and customize therapy. Now, extended induction ought to be seen as a logical, scientifically supported part of customized tofacitinib treatment.
Publish Date 2026-02-27 08:35
Citation

Fouad Y, Aboelela AS. Lessons from extended induction and practical evidence for improving tofacitinib therapy in ulcerative colitis. World J Gastroenterol 2026; 32(9): 115785

URL https://www.wjgnet.com/1007-9327/full/v32/i9/115785.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i9.115785
Full Article (PDF) WJG-32-115785-with-cover.pdf
Manuscript File 115785_Auto_Edited_072311.docx
Answering Reviewers 115785-answering-reviewers.pdf
Audio Core Tip 115785-audio.m4a
Conflict-of-Interest Disclosure Form 115785-conflict-of-interest-statement.pdf
Copyright License Agreement 115785-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115785-non-native-speakers.pdf
Peer-review Report 115785-peer-reviews.pdf
Scientific Misconduct Check 115785-scientific-misconduct-check.png
Scientific Editor Work List 115785-scientific-editor-work-list.pdf
CrossCheck Report 115785-crosscheck-report.pdf