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Articles Published Processes
4/3/2026 6:41:51 AM | Browse: 29 | Download: 79
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Received |
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2025-10-31 13:38 |
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Peer-Review Started |
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2025-10-31 13:39 |
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First Decision by Editorial Office Director |
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2025-11-19 11:01 |
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Return for Revision |
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2025-11-19 11:01 |
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Revised |
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2025-12-02 04:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-29 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-29 07:07 |
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Articles in Press |
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2026-01-29 07:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-24 00:41 |
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Publish the Manuscript Online |
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2026-04-03 06:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Optimal strategies for mitigating gastrointestinal bleeding in patients receiving antiplatelet therapy: Real-world study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Minjee Kim, Sang Ah Chi, Ji Eun Kim, Eun Ran Kim, Sung Noh Hong, Young-Ho Kim, Kyunga Kim and Dong Kyung Chang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dong Kyung Chang, Professor, Department of Medicine, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea. do.chang@samsung.com |
| Key Words |
Gastrointestinal bleeding; Aspirin; Clopidogrel; Proton pump inhibitor; Rebamipide; Antiplatelet therapy; High risk; Low risk; Protective agents; Real-world study |
| Core Tip |
Aspirin and clopidogrel increase the risk of gastrointestinal bleeding; however, the comparative effectiveness of these mucosal protective agents remains unclear. In a large real-world cohort, we found that proton pump inhibitor monotherapy provided substantial protection, whereas combination therapy with rebamipide offered the greatest risk reduction, particularly in high-risk patients. No significant benefit was observed in clopidogrel-alone users or low-risk populations. These findings support a personalized, risk-stratified approach to gastroprotection, and suggest that combination mucosal protective strategies may provide incremental benefits beyond standard regimens. |
| Publish Date |
2026-04-03 06:41 |
| Citation |
Kim M, Chi SA, Kim JE, Kim ER, Hong SN, Kim YH, Kim K, Chang DK. Optimal strategies for mitigating gastrointestinal bleeding in patients receiving antiplatelet therapy: Real-world study. World J Gastroenterol 2026; 32(14): 115790 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i14/115790.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i14.115790 |
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