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Articles Published Processes
5/11/2026 9:00:23 AM | Browse: 11 | Download: 17
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Received |
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2025-10-27 01:42 |
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Peer-Review Started |
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2025-10-27 08:58 |
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First Decision by Editorial Office Director |
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2025-12-03 10:01 |
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Return for Revision |
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2025-12-03 10:01 |
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Revised |
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2025-12-15 05:49 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-31 02:31 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-31 03:37 |
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Articles in Press |
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2025-12-31 03:37 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-01 06:28 |
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Publish the Manuscript Online |
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2026-05-11 09:00 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Indirect bilirubin: A potential predictive biomarker for diabetic retinopathy and its clinical translational potential
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhao Zhang, Xiao-Qian Shan, Feng-Ming Liang and Li-Xia Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82174442 |
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| Corresponding Author |
Li-Xia Zhang, . zhanglixia77@126.com |
| Key Words |
Biomarker; Diabetic retinopathy; Indirect bilirubin; Type 2 diabetes mellitus |
| Core Tip |
Diabetic retinopathy (DR) remains a leading cause of vision loss and blindness among individuals with type 2 diabetes. A critical need exists for reliable biomarkers that can facilitate early identification and diagnosis of DR, as the absence of such markers significantly impedes timely intervention and effective management. The study by Lin et al reveals that "IBIL levels are independently and inversely associated with DR risk, suggesting its potential as a low-cost, non-invasive, and readily applicable predictive biomarker". To facilitate a comprehensive understanding of this novel predictive indicator, this review first evaluates the potential of indirect bilirubin in DR risk prediction from both basic science and clinical perspectives. It subsequently addresses the advantages and challenges associated with its application as a predictive biomarker and concludes with projections on its future role in DR screening strategies. |
| Publish Date |
2026-05-11 09:00 |
| Citation |
Zhang Z, Shan XQ, Liang FM, Zhang LX. Letter to the Editor: Indirect bilirubin: A potential predictive biomarker for diabetic retinopathy and its clinical translational potential. World J Diabetes 2026; 17(5): 115813 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i5/115813.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i5.115813 |
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