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2/10/2026 6:02:07 AM | Browse: 4 | Download: 20
Publication Name World Journal of Clinical Cases
Manuscript ID 115814
Country Morocco
Received
2025-10-27 07:39
Peer-Review Started
2025-10-27 07:40
First Decision by Editorial Office Director
2026-01-08 03:49
Return for Revision
2026-01-08 03:49
Revised
2026-01-15 15:34
Publication Fee Transferred
Second Decision by Editor
2026-02-04 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-04 07:18
Articles in Press
2026-02-04 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-06 02:02
Publish the Manuscript Online
2026-02-10 06:02
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Letter to the Editor
Article Title Human leukocyte antigen variants and clinical features of primary biliary cholangitis: Cumulative contributions
Manuscript Source Invited Manuscript
All Author List Abdellatif Bouayad
ORCID
Author(s) ORCID Number
Abdellatif Bouayad http://orcid.org/0000-0003-4377-0833
Funding Agency and Grant Number
Corresponding Author Abdellatif Bouayad, Associate Professor, MD, Department of Immunology, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, 4867 Oujda l’Université, Oujda 60049, Morocco. a.bouayad@ump.ac.ma
Key Words Human leukocyte antigen class II; Human leukocyte antigen-G; Primary biliary cholangitis; Prognosis; Primary biliary cholangitis-autoimmune hepatitis overlap syndrome; Therapy response
Core Tip Specific classical human leukocyte antigen (HLA) alleles and haplotypes may influence predisposition to primary biliary cholangitis (PBC), prognosis, and the development of PBC-autoimmune hepatitis overlap syndrome. Potential cumulative contributions between the non-classical HLA-G*01: 01: 01: 08-UTR-1 haplotype and its soluble HLA-G molecules may predict a poor therapeutic response to ursodeoxycholic acid. Thus, soluble HLA-G molecules may serve as novel, non-invasive biomarkers to guide personalized PBC treatment.
Publish Date 2026-02-10 06:02
Citation

Bouayad A. Human leukocyte antigen variants and clinical features of primary biliary cholangitis: Cumulative contributions. World J Clin Cases 2026; 12(5): 115814

URL https://www.wjgnet.com/2307-8960/full/v14/i5/115814.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i5.115814
Full Article (PDF) WJCC-14-115814-with-cover.pdf
Manuscript File 115814_Auto_Edited_092514.docx
Answering Reviewers 115814-answering-reviewers.pdf
Audio Core Tip 115814-audio.mp3
Conflict-of-Interest Disclosure Form 115814-conflict-of-interest-statement.pdf
Copyright License Agreement 115814-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115814-non-native-speakers.pdf
Peer-review Report 115814-peer-reviews.pdf
Scientific Misconduct Check 115814-scientific-misconduct-check.png
Scientific Editor Work List 115814-scientific-editor-work-list.pdf
CrossCheck Report 115814-crosscheck-report.pdf