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Articles Published Processes
5/27/2026 1:22:03 PM | Browse: 1 | Download: 0
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Received |
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2025-10-27 13:26 |
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Peer-Review Started |
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2025-10-27 13:28 |
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First Decision by Editorial Office Director |
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2025-11-05 06:01 |
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Return for Revision |
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2025-11-05 06:01 |
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Revised |
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2025-11-19 21:50 |
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Publication Fee Transferred |
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2025-12-03 21:05 |
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Second Decision by Editor |
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2026-02-14 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-14 08:10 |
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Articles in Press |
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2026-02-14 08:10 |
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Edit the Manuscript by Language Editor |
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2026-02-27 22:55 |
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Typeset the Manuscript |
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2026-04-13 01:46 |
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Publish the Manuscript Online |
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2026-05-27 13:22 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Mucinous rectal adenocarcinoma and neoadjuvant therapy: Implications for surgical practice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Alberto Patriti, Francesco Graziano and Rita Chiari |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Alberto Patriti, MD, PhD, Department of Surgery, Division of General and Robotic Surgery, Azienda Sanitaria Territoriale di Pesaro-Urbino, Ospedale San Salvatore Piazzale Cinelli, 1, Pesaro 61121, Italy. albertopatriti@gmail.com |
| Key Words |
Rectal cancer; Mucinous adenocarcinoma; Total mesorectal excision; Surgery; Total neoadjuvant therapy; Radiotherapy; Multivisceral resection; Watch-and-Wait |
| Core Tip |
Mucinous adenocarcinoma (MAC) is a distinct histologic subtype characterized by abundant extracellular mucin and a reduced response to neoadjuvant chemoradiotherapy or total neoadjuvant therapy (TNT). This review integrates molecular, radiologic, and surgical evidence to explain why MAC behaves differently and how meticulous total mesorectal excision can mitigate these challenges. When tumor downstaging and complete (R0) resection are achieved after TNT, long-term outcomes may be comparable to non-MAC, underscoring the importance of surgical precision and multidisciplinary planning. |
| Publish Date |
2026-05-27 13:22 |
| Citation |
Patriti A, Graziano F, Chiari R. Mucinous rectal adenocarcinoma and neoadjuvant therapy: Implications for surgical practice. World J Gastrointest Surg 2026; 18(5): 115825 |
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i5/115825.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v18.i5.115825 |
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