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3/12/2026 12:25:35 PM | Browse: 2 | Download: 10
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 115835
Country Greece
Received
2025-10-27 07:47
Peer-Review Started
2025-10-27 07:48
First Decision by Editorial Office Director
2025-11-05 07:46
Return for Revision
2025-11-05 07:46
Revised
2025-11-16 20:18
Publication Fee Transferred
Second Decision by Editor
2025-12-23 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-23 08:49
Articles in Press
2025-12-23 08:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-26 02:03
Publish the Manuscript Online
2026-03-12 12:25
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title From bench to bedside: Stem cell applications in gastric cancer therapy and their emerging clinical relevance
Manuscript Source Invited Manuscript
All Author List Ioana A Prisacariu, Konstantinos E Koumarelas, Panagiotis Papadopoulos, Dimitrios Schizas and Grigorios Christodoulidis
ORCID
Author(s) ORCID Number
Konstantinos E Koumarelas http://orcid.org/0000-0002-5614-4770
Dimitrios Schizas http://orcid.org/0000-0002-7046-0112
Grigorios Christodoulidis http://orcid.org/0000-0003-3413-0666
Funding Agency and Grant Number
Corresponding Author Grigorios Christodoulidis, MD, PhD, Department of General Surgery, University Hospital of Larissa, Mezourlo, Larissa 41110, Thessalia, Greece. gregsurg@yahoo.gr
Key Words Gastric cancer; Gastric cancer stem cells; Stemness; Tumor microenvironment; Therapy resistance; Biomarkers; Precision medicine
Core Tip Gastric cancer stem cells (GCSCs) are key mediators of recurrence, metastasis, and therapy resistance. Understanding their regulation through signaling pathways, epigenetic mechanisms, and tumor microenvironmental support provides opportunities for novel therapeutic interventions. This review highlights the clinical relevance of GCSCs, current mechanistic insights, and emerging strategies such as RNA-based therapies, immunotherapy, and nanotechnology offering a precision medicine framework to improve outcomes in gastric cancer.
Publish Date 2026-03-12 12:25
Citation

Prisacariu IA, Koumarelas KE, Papadopoulos P, Schizas D, Christodoulidis G. From bench to bedside: Stem cell applications in gastric cancer therapy and their emerging clinical relevance. World J Gastrointest Oncol 2026; 18(3): 115835

URL https://www.wjgnet.com/1948-5204/full/v18/i3/115835.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i3.115835
Full Article (PDF) WJGO-18-115835-with-cover.pdf
Manuscript File 115835_Auto_Edited_105047.docx
Answering Reviewers 115835-answering-reviewers.pdf
Audio Core Tip 115835-audio.m4a
Conflict-of-Interest Disclosure Form 115835-conflict-of-interest-statement.pdf
Copyright License Agreement 115835-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115835-non-native-speakers.pdf
Peer-review Report 115835-peer-reviews.pdf
Scientific Misconduct Check 115835-scientific-misconduct-check.png
Scientific Editor Work List 115835-scientific-editor-work-list.pdf
CrossCheck Report 115835-crosscheck-report.pdf