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Articles Published Processes
1/5/2026 6:55:12 AM | Browse: 7 | Download: 15
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Received |
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2025-11-07 09:18 |
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Peer-Review Started |
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2025-11-07 09:18 |
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First Decision by Editorial Office Director |
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2025-11-18 09:58 |
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Return for Revision |
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2025-11-18 09:58 |
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Revised |
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2025-12-01 07:41 |
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Publication Fee Transferred |
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2025-12-08 15:09 |
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Second Decision by Editor |
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2025-12-22 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-22 09:45 |
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Articles in Press |
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2025-12-22 09:45 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-04 00:34 |
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Publish the Manuscript Online |
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2026-01-05 06:55 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Case Report |
| Article Title |
Preterm heart failure and refractory lactic acidosis caused by congenital hypothyroidism: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Ju Chen, Jiao Li, Xiao-Ming Xu, Bo Zhang, Bo-Chao Cheng and Jing Shi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Clinical Research Funding of West China Second University Hospital, Sichuan University |
KL075 |
| Xizang Autonomous Region Science and Technology Program |
XZ202501JD0017 |
| National Natural Science Foundation of China |
81501304 |
| Sichuan Science and Technology Program |
22ZDYF0831 |
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| Corresponding Author |
Jing Shi, PhD, Department of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, section 3, Renmin South Road, Wuhou District, Chengdu 610041, Sichuan Province, China. shijing@scu.edu.cn |
| Key Words |
Congenital hypothyroidism; Lactic acidosis; Heart failure; Neonate; Preterm; Case report |
| Core Tip |
This report details a critical case of congenital hypothyroidism in a preterm infant, presenting as severe heart failure and refractory lactic acidosis. The infant showed a rapid, life-saving response to levothyroxine, highlighting congenital hypothyroidism’s role as a reversible cause of cardiovascular collapse. A key novelty is the profound lactic acidosis, a rarely reported feature of neonatal hypothyroidism. This case underscores the need for high clinical suspicion and repeat screening in preterm infants with unexplained heart failure or metabolic acidosis. Our findings advance understanding of thyroid hormones’ role in cardiac metabolism and confirm that prompt treatment is vital for excellent outcomes. |
| Publish Date |
2026-01-05 06:55 |
| Citation |
Chen HJ, Li J, Xu XM, Zhang B, Cheng BC, Shi J. Preterm heart failure and refractory lactic acidosis caused by congenital hypothyroidism: A case report and review of literature. World J Clin Cases 2026; 14(1): 115845 |
| URL |
https://www.wjgnet.com/2307-8960/full/v14/i1/115845.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v14.i1.115845 |
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