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3/16/2026 8:22:55 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115846
Country China
Received
2025-10-27 04:18
Peer-Review Started
2025-10-27 04:18
First Decision by Editorial Office Director
2025-11-19 10:57
Return for Revision
2025-11-19 10:57
Revised
2025-12-02 15:26
Publication Fee Transferred
Second Decision by Editor
2026-01-14 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-14 07:07
Articles in Press
2026-01-14 07:07
Edit the Manuscript by Language Editor
2026-01-19 17:21
Typeset the Manuscript
2026-02-28 08:52
Publish the Manuscript Online
2026-03-16 08:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Research progress on co-morbidity between gastrointestinal and pulmonary diseases from the perspective of the gut-lung axis
Manuscript Source Invited Manuscript
All Author List Hao-Jun Huang, Pan-Pan Liu and De-Feng Dong
ORCID
Author(s) ORCID Number
Hao-Jun Huang http://orcid.org/0009-0007-4309-7761
Funding Agency and Grant Number
Corresponding Author Hao-Jun Huang, School of Nursing, Yanbian University, No. 977 Gongyuan Road, Yanji 133000, Jilin Province, China. hy86382211@163.com
Key Words Microbiota; Comorbidity mechanism; Lung diseases; Gastrointestinal diseases; Gut-lung axis
Core Tip The gut-lung axis represents a bidirectional communication network that links the gastrointestinal and respiratory systems through microbial, immune, and metabolic pathways. This review synthesizes recent advances in understanding how gut dysbiosis, microbial translocation, immune dysregulation, and epigenetic modifications contribute to gastrointestinal-pulmonary comorbidities. We highlight key clinical phenotypes and explore emerging therapeutic strategies, including microbiota-targeted interventions, metabolite supplementation, and immune modulation. Future efforts should emphasize multi-omics integration, organoid-based models, and AI-driven predictive analytics to advance precision medicine anchored in the gut-lung axis.
Publish Date 2026-03-16 08:22
Citation

Huang HJ, Liu PP, Dong DF. Research progress on co-morbidity between gastrointestinal and pulmonary diseases from the perspective of the gut-lung axis. World J Gastroenterol 2026; 32(11): 115846

URL https://www.wjgnet.com/1007-9327/full/v32/i11/115846.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i11.115846
Full Article (PDF) WJG-32-115846-with-cover.pdf
Manuscript File 115846_Auto_Edited_074454.docx
Answering Reviewers 115846-answering-reviewers.pdf
Audio Core Tip 115846-audio.m4a
Conflict-of-Interest Disclosure Form 115846-conflict-of-interest-statement.pdf
Copyright License Agreement 115846-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115846-non-native-speakers.pdf
Peer-review Report 115846-peer-reviews.pdf
Scientific Misconduct Check 115846-scientific-misconduct-check.png
Scientific Editor Work List 115846-scientific-editor-work-list.pdf
CrossCheck Report 115846-crosscheck-report.pdf