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Articles Published Processes
5/18/2026 10:29:13 AM | Browse: 2 | Download: 0
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Received |
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2025-10-29 13:21 |
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Peer-Review Started |
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2025-10-29 13:22 |
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First Decision by Editorial Office Director |
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2025-12-12 09:16 |
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Return for Revision |
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2025-12-12 09:16 |
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Revised |
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2025-12-20 19:45 |
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Publication Fee Transferred |
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2025-12-23 01:52 |
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Second Decision by Editor |
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2026-03-05 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-05 09:15 |
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Articles in Press |
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2026-03-05 09:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-29 02:08 |
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Publish the Manuscript Online |
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2026-05-18 10:29 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Branch duct intraductal papillary mucinous neoplasms: How ready are we to de-escalate surveillance?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Phillip J Hopley, Philip Whelan, Richard Jackson, Jonathan Evans, Timothy Andrews, Paula Ghaneh, Michael Raraty, William Greenhalf and Christopher M Halloran |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Christopher M Halloran, FRCS, MD, Professor, Department of Pancreatic Surgery, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon Street, Liverpool L7 8YE, United Kingdom. halloran@liverpool.ac.uk |
| Key Words |
Intraductal pancreatic mucinous neoplasm; Branch duct intraductal papillary mucinous neoplasm; Surveillance; Pancreatic ductal adenocarcinoma; De-escalation; Cancer antigen 19-9; Fitness |
| Core Tip |
This study reports outcomes of 1191 participants with branch duct intraductal papillary mucinous neoplasm under surveillance. There are three important findings: Firstly, surgery is front loaded and the opportunity to resect pancreatic ductal adenocarcinoma appears to occur early in surveillance. Secondly, the incremental return of continued investigations, resulting in risk reducing surgery, dramatically diminishes after two years. Lastly, patients who have been in surveillance for more than two years with a serum cancer antigen 19-9 < 43 KU/L and branch duct intraductal papillary mucinous neoplasm stability at < 30 mm have low rates of malignant transformation and surveillance can be de-escalated, with discharge considered at five years. |
| Publish Date |
2026-05-18 10:29 |
| Citation |
Hopley PJ, Whelan P, Jackson R, Evans J, Andrews T, Ghaneh P, Raraty M, Greenhalf W, Halloran CM. Branch duct intraductal papillary mucinous neoplasms: How ready are we to de-escalate surveillance? World J Gastroenterol 2026; 32(19): 115852 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i19/115852.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i19.115852 |
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