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Publication Name World Journal of Transplantation
Manuscript ID 115879
Country Argentina
Received
2025-10-28 06:39
Peer-Review Started
2025-10-28 06:39
First Decision by Editorial Office Director
2025-11-05 08:58
Return for Revision
2025-11-05 08:58
Revised
2025-11-19 12:48
Publication Fee Transferred
Second Decision by Editor
2026-02-03 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 09:33
Articles in Press
2026-02-03 09:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-30 14:32
Publish the Manuscript Online
2026-05-29 08:41
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Editorial
Article Title Multifaceted role of histopathology in liver transplantation for hepatocellular carcinoma: A narrative review towards precision prognosis
Manuscript Source Invited Manuscript
All Author List Marcelo Fabián Amante, María Fernanda Vargas Wille and María L Pestalardo
ORCID
Author(s) ORCID Number
Marcelo Fabián Amante http://orcid.org/0000-0002-0237-0713
María Fernanda Vargas Wille http://orcid.org/0000-0001-7674-4266
María L Pestalardo http://orcid.org/0009-0002-9451-213X
Funding Agency and Grant Number
Corresponding Author Marcelo Fabián Amante, Department of División Patología, Hospital General de Agudos Cosme Argerich, Pi y Margall 480, Buenos Aires C1155AHA, Ciudad Autónoma de, Argentina. marcelofabianamante@gmail.com
Key Words Hepatocellular carcinoma; Liver transplantation; Histopathology; Vascular invasion; Tumor differentiation; Prognostic stratification; Precision medicine
Core Tip Histopathological assessment remains indispensable for liver transplantation in hepatocellular carcinoma, providing crucial information about tumor biology that imaging alone cannot capture. This editorial emphasizes how vascular invasion, tumor differentiation, and histologic subtyping critically refine prognostic stratification and guide individualized post-transplant management. By integrating standardized sampling with digital pathology and molecular profiling, pathology evolves from a diagnostic discipline into a predictive and decision-shaping science, optimizing organ allocation for hepatocellular carcinoma transplantation and improving long-term outcomes for patients.
Publish Date 2026-05-29 08:41
Citation

Amante MF, Vargas Wille MF, Pestalardo ML. Multifaceted role of histopathology in liver transplantation for hepatocellular carcinoma: A narrative review towards precision prognosis. World J Transplant 2026; 16(2): 115879

URL https://www.wjgnet.com/2220-3230/full/v16/i2/115879.htm
DOI https://dx.doi.org/10.5500/wjt.v16.i2.115879
Full Article (PDF) WJT-16-115879-with-cover.pdf
Manuscript File 115879_Auto_Edited-YJP.docx
Answering Reviewers 115879-answering-reviewers.pdf
Audio Core Tip 115879-audio.m4a
Conflict-of-Interest Disclosure Form 115879-conflict-of-interest-statement.PDF
Copyright License Agreement 115879-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115879-non-native-speakers.pdf
Peer-review Report 115879-peer-reviews.pdf
Scientific Misconduct Check 115879-scientific-misconduct-check.png
Scientific Editor Work List 115879-scientific-editor-work-list.pdf
CrossCheck Report 115879-crosscheck-report.pdf