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2/3/2026 6:28:04 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 115944
Country Türkiye
Received
2025-10-29 05:42
Peer-Review Started
2025-10-29 05:43
First Decision by Editorial Office Director
2025-11-06 08:51
Return for Revision
2025-11-06 08:51
Revised
2025-11-17 14:52
Publication Fee Transferred
Second Decision by Editor
2025-12-09 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-10 02:35
Articles in Press
2025-12-10 02:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-26 15:36
Publish the Manuscript Online
2026-02-03 06:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Editorial
Article Title Does anesthesia choice shape oncologic destiny in gastric cancer surgery?
Manuscript Source Invited Manuscript
All Author List Oguzhan Arun and Funda Arun
ORCID
Author(s) ORCID Number
Oguzhan Arun http://orcid.org/0000-0001-6101-1481
Funda Arun http://orcid.org/0000-0001-7345-0318
Funding Agency and Grant Number
Corresponding Author Oguzhan Arun, MD, PhD, Professor, Department of Anesthesiology and Reanimation, Selcuk University Faculty of Medicine, Alaaddin Keykubat Kampus, Konya 42130, Türkiye. oguzarun@selcuk.edu.tr
Key Words Anesthesia; Gastric cancer; Propofol; Sevoflurane; Total intravenous anesthesia
Core Tip Anesthetic choice in gastric cancer surgery extends beyond technical preference, potentially influencing immune function, stress response, and oncologic outcomes. Propofol-based total intravenous anesthesia demonstrates promising molecular and clinical anti-tumor properties-modulating microRNAs, enhancing natural killer cell activity, and improving post-operative recovery-while sevoflurane, though traditionally considered neutral, shows emerging immunoregulatory and gene-expression effects. Current evidence, including the recent Wang et al study, suggests both agents yield comparable perioperative safety and survival outcomes; however, their distinct molecular profiles highlight anesthesia as a modifiable element in personalized cancer care. Future biomarker-driven research is essential to clarify when and how anesthetic selection might influence long-term oncologic prognosis.
Publish Date 2026-02-03 06:28
Citation

Arun O, Arun F. Does anesthesia choice shape oncologic destiny in gastric cancer surgery? World J Gastrointest Oncol 2026; 18(2): 115944

URL https://www.wjgnet.com/1948-5204/full/v18/i2/115944.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i2.115944
Full Article (PDF) WJGO-18-115944-with-cover.pdf
Manuscript File 115944_Auto_Edited_022151.docx
Answering Reviewers 115944-answering-reviewers.pdf
Audio Core Tip 115944-audio.m4a
Conflict-of-Interest Disclosure Form 115944-conflict-of-interest-statement.pdf
Copyright License Agreement 115944-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115944-non-native-speakers.pdf
Peer-review Report 115944-peer-reviews.pdf
Scientific Misconduct Check 115944-scientific-misconduct-check.png
Scientific Editor Work List 115944-scientific-editor-work-list.pdf
CrossCheck Report 115944-crosscheck-report.pdf