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3/2/2026 8:37:14 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115957
Country China
Received
2025-11-03 07:47
Peer-Review Started
2025-11-03 07:47
First Decision by Editorial Office Director
2025-11-21 10:09
Return for Revision
2025-11-21 10:09
Revised
2025-12-04 02:14
Publication Fee Transferred
2025-12-05 01:38
Second Decision by Editor
2026-01-07 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-07 08:30
Articles in Press
2026-01-07 08:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-13 02:36
Publish the Manuscript Online
2026-03-02 08:37
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Chaihu-Shugan-San ameliorates chronic atrophic gastritis by inhibiting nuclear factor-kappa B-mediated inflammation and apoptosis
Manuscript Source Unsolicited Manuscript
All Author List Jin Song, Dan-Yan Li, Xiao-Li Zhang, Sha-Sha He, Ning Wang, Hui-Cun Zhang, Yun-Jing Bai, Bo Li and Sheng-Sheng Zhang
ORCID
Author(s) ORCID Number
Jin Song http://orcid.org/0000-0002-4513-4622
Bo Li http://orcid.org/0000-0002-4857-6610
Sheng-Sheng Zhang http://orcid.org/0000-0003-0457-1727
Funding Agency and Grant Number
Funding Agency Grant Number
Special Funds of Beijing Institute of Chinese Medicine No. YJS-2024-20
Corresponding Author Sheng-Sheng Zhang, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23 Meishuguanhoujie, Dongcheng District, Beijing 100010, China. zhss2000@hotmail.com
Key Words Chronic atrophic gastritis; Chaihu-Shugan-San; Inflammation; Apoptosis; Nuclear factor-kappa B
Core Tip Our study demonstrated that Chaihu-Shugan-San (CSS) restored body weight, mitigated gastric tissue histology, and alleviated intestinal metaplasia in rats with chronic atrophic gastritis, reduced levels of inflammatory cytokines, and promoted antiapoptotic pathways. CSS was shown to downregulate the nuclear factor-kappa B signaling proteins, providing insights into its mechanism of action in protection against chronic atrophic gastritis development.
Publish Date 2026-03-02 08:37
Citation

Song J, Li DY, Zhang XL, He SS, Wang N, Zhang HC, Bai YJ, Li B, Zhang SS. Chaihu-Shugan-San ameliorates chronic atrophic gastritis by inhibiting nuclear factor-kappa B-mediated inflammation and apoptosis. World J Gastroenterol 2026; 32(10): 115957

URL https://www.wjgnet.com/1007-9327/full/v32/i10/115957.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i10.115957
Full Article (PDF) WJG-32-115957-with-cover.pdf
The ARRIVE Guidelines 115957-The-ARRIVE-Guidelines.pdf
Manuscript File 115957_Auto_Edited_072124.docx
Answering Reviewers 115957-answering-reviewers.pdf
Audio Core Tip 115957-audio.m4a
Biostatistics Review Certificate 115957-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115957-conflict-of-interest-statement.pdf
Copyright License Agreement 115957-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 115957-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 115957-non-native-speakers.pdf
Supplementary Material 115957-supplementary-material.pdf
Peer-review Report 115957-peer-reviews.pdf
Scientific Misconduct Check 115957-scientific-misconduct-check.png
Scientific Editor Work List 115957-scientific-editor-work-list.pdf
CrossCheck Report 115957-crosscheck-report.pdf