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Articles Published Processes
3/30/2026 8:58:29 AM | Browse: 34 | Download: 137
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Received |
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2025-11-18 09:25 |
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Peer-Review Started |
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2025-11-18 09:25 |
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First Decision by Editorial Office Director |
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2025-12-05 06:56 |
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Return for Revision |
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2025-12-05 06:56 |
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Revised |
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2025-12-21 07:29 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-09 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-09 06:18 |
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Articles in Press |
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2026-01-09 06:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-16 09:48 |
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Publish the Manuscript Online |
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2026-03-30 08:58 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology |
| Manuscript Type |
Basic Study |
| Article Title |
Yueju pill regulates the mechanism of SIRT1/FoxO3a-mediated autophagy pathway against depression
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Li Gao, An-Wen Huang, Da He, Jia-Zhen Tong, Wei-Feng Hong, Xu-Jie Zhuang, Xin-Ming Wu, Yang-Hui Zhou and Min Lin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare (Minweirenhan 2023) |
26 |
| the Medical Innovation Project of Fujian Provincial Health Commission |
2022CXA052 |
| the Fujian University of Traditional Chinese Medicine Major Scientific and Technological Innovation “Open Competition Mechanism to Select the Best Candidates” Special Project |
XJB2022003-3 |
| the Natural Science Foundation of Fujian Province |
2024J01733 |
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| Corresponding Author |
Li-Li Gao, PhD, Department of Neurology, The second Affiliated Hospital of Fujian Traditional Chinese Medical University, No. 282, Wusi Road, Fuzhou 350003, Fujian Province, China. gaolili2025@yeah.net |
| Key Words |
Yueju pill; Chronic unpredictable mild stress; SIRT1/FoxO3a; Autophagy; Antidepressant |
| Core Tip |
Depression is a mental disorder primarily characterized by low mood, with a gradually increasing incidence in modern society. The exploration of antidepressants derived from traditional Chinese medicinal substances has therefore become a research hotspot. Although previous studies indicate that Yueju pill is effective in treating mood disorder-related syndromes, its potential antidepressant mechanism via regulation of the SIRT1/FoxO3a-mediated autophagy pathway has not been reported. Therefore, this study employed a chronic unpredictable mild stress rat model and investigated the antidepressant mechanism of Yueju pill through targeted pathway intervention. |
| Publish Date |
2026-03-30 08:58 |
| Citation |
Gao LL, Huang AW, He D, Tong JZ, Hong WF, Zhuang XJ, Wu XM, Zhou YH, Lin M. Yueju pill regulates the mechanism of SIRT1/FoxO3a-mediated autophagy pathway against depression. World J Psychiatry 2026; 16(4): 115960
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i4/115960.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i4.115960 |
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