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3/30/2026 8:58:29 AM | Browse: 0 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 115960
Country China
Received
2025-11-18 09:25
Peer-Review Started
2025-11-18 09:25
First Decision by Editorial Office Director
2025-12-05 06:56
Return for Revision
2025-12-05 06:56
Revised
2025-12-21 07:29
Publication Fee Transferred
Second Decision by Editor
2026-01-09 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-09 06:18
Articles in Press
2026-01-09 06:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-16 09:48
Publish the Manuscript Online
2026-03-30 08:58
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Basic Study
Article Title Yueju pill regulates the mechanism of SIRT1/FoxO3a-mediated autophagy pathway against depression
Manuscript Source Unsolicited Manuscript
All Author List Li-Li Gao, An-Wen Huang, Da He, Jia-Zhen Tong, Wei-Feng Hong, Xu-Jie Zhuang, Xin-Ming Wu, Yang-Hui Zhou and Min Lin
ORCID
Author(s) ORCID Number
Li-Li Gao http://orcid.org/0009-0006-5137-5760
Funding Agency and Grant Number
Funding Agency Grant Number
the Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare (Minweirenhan 2023) 26
the Medical Innovation Project of Fujian Provincial Health Commission 2022CXA052
the Fujian University of Traditional Chinese Medicine Major Scientific and Technological Innovation “Open Competition Mechanism to Select the Best Candidates” Special Project XJB2022003-3
the Natural Science Foundation of Fujian Province 2024J01733
Corresponding Author Li-Li Gao, PhD, Department of Neurology, The second Affiliated Hospital of Fujian Traditional Chinese Medical University, No. 282, Wusi Road, Fuzhou 350003, Fujian Province, China. gaolili2025@yeah.net
Key Words Yueju pill; Chronic unpredictable mild stress; SIRT1/FoxO3a; Autophagy; Antidepressant
Core Tip Depression is a mental disorder primarily characterized by low mood, with a gradually increasing incidence in modern society. The exploration of antidepressants derived from traditional Chinese medicinal substances has therefore become a research hotspot. Although previous studies indicate that Yueju pill is effective in treating mood disorder-related syndromes, its potential antidepressant mechanism via regulation of the SIRT1/FoxO3a-mediated autophagy pathway has not been reported. Therefore, this study employed a chronic unpredictable mild stress rat model and investigated the antidepressant mechanism of Yueju pill through targeted pathway intervention.
Publish Date 2026-03-30 08:58
Citation

Gao LL, Huang AW, He D, Tong JZ, Hong WF, Zhuang XJ, Wu XM, Zhou YH, Lin M. Yueju pill regulates the mechanism of SIRT1/FoxO3a-mediated autophagy pathway against depression. World J Psychiatry 2026; 16(4): 115960

URL https://www.wjgnet.com/2220-3206/full/v16/i4/115960.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i4.115960
Full Article (PDF) WJP-16-115960-with-cover.pdf
The ARRIVE Guidelines 115960-The-ARRIVE-Guidelines.pdf
Manuscript File 115960_Auto_Edited_090220.docx
Answering Reviewers 115960-answering-reviewers.pdf
Audio Core Tip 115960-audio.mp3
Biostatistics Review Certificate 115960-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115960-conflict-of-interest-statement.pdf
Copyright License Agreement 115960-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 115960-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 115960-non-native-speakers.pdf
Peer-review Report 115960-peer-reviews.pdf
Scientific Misconduct Check 115960-scientific-misconduct-check.png
Scientific Editor Work List 115960-scientific-editor-work-list.pdf
CrossCheck Report 115960-crosscheck-report.pdf