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Articles Published Processes
4/24/2026 5:43:48 AM | Browse: 1 | Download: 1
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Received |
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2025-10-31 05:37 |
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Peer-Review Started |
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2025-10-31 05:38 |
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First Decision by Editorial Office Director |
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2025-11-19 11:00 |
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Return for Revision |
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2025-11-19 11:00 |
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Revised |
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2025-12-03 10:27 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-12 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-12 12:47 |
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Articles in Press |
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2026-01-12 12:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-28 08:54 |
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Publish the Manuscript Online |
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2026-04-24 05:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Rethinking Helicobacter pylori culture - toward precision media for a fastidious pathogen
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cheng-Fei Zhao, Xiao-Ting Xu, Shen-Yi Ye, Tian-Hui Liu and Zhi-Feng Xu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province |
2023J01160 |
| Scientific Research Project of Putian University |
2022059 |
| Special Project for Outstanding Young Talents of Putian University |
2024072 |
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| Corresponding Author |
Zhi-Feng Xu, Chief Physician, Department of Cardiothoracic Surgery, The 95th Hospital of Putian, No. 485 Dongyan Road, Licheng District, Putian 351100, Fujian Province, China. zhifengxu1972@163.com |
| Key Words |
Reproducibility; Host-microbe; Precision microbiology; Fastidious pathogen; Precision media; Helicobacter pylori |
| Core Tip |
Cultivating Helicobacter pylori (H. pylori) remains one of persistent challenges in microbiology due to its stringent nutritional and microaerophilic growth requirements. A recent comparative study across ten liquid media and nine H. pylori strains demonstrated that growth efficiency is highly dependent on both medium composition and strain-specific characteristics. Chopped meat carbohydrate broth, Columbia broth (CB), and fastidious anaerobe broth supported significantly better growth than conventional Brucella broth. These findings underscore that culture media are not passive substrates but active determinants of microbial physiology. An ideal precision medium should be defined not only by its ability to support high biomass but also by its capacity to maintain H. pylori in its viable, spiral form. Such optimization may improve experimental reproducibility and facilitate advances in diagnostics, antimicrobial susceptibility testing, and vaccine development. |
| Publish Date |
2026-04-24 05:43 |
| Citation |
Zhao CF, Xu XT, Ye SY, Liu TH, Xu ZF. Letter to the Editor: Rethinking Helicobacter pylori culture - toward precision media for a fastidious pathogen. World J Gastroenterol 2026; 32(17): 115984 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i17/115984.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i17.115984 |
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