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6/25/2026 8:21:21 AM | Browse: 1 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 116004
Country China
Received
2025-11-25 09:06
Peer-Review Started
2025-11-25 09:06
First Decision by Editorial Office Director
2025-12-16 06:41
Return for Revision
2025-12-16 06:41
Revised
2026-01-07 11:20
Publication Fee Transferred
2026-01-29 10:10
Second Decision by Editor
2026-03-09 02:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-17 10:32
Articles in Press
2026-03-17 10:32
Edit the Manuscript by Language Editor
2026-03-27 22:17
Typeset the Manuscript
2026-05-22 03:07
Publish the Manuscript Online
2026-06-25 08:21
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title Dysregulated circARF3/miR-27b-3p/YAP1 axis contributes to impaired osteogenic differentiation of periodontal ligament stem cells in periodontitis
Manuscript Source Unsolicited Manuscript
All Author List Lin Qi, Xiao-Qing Wang, Jia Sun, Rui-Zhi Li and Ze-Bin Mao
ORCID
Author(s) ORCID Number
Lin Qi http://orcid.org/0009-0008-5236-9164
Ze-Bin Mao http://orcid.org/0009-0000-8759-2704
Funding Agency and Grant Number
Corresponding Author Ze-Bin Mao, Department of Biochemistry and Biophysics, School of Basic Medical Sciences Peking University, No. 38 Xueyuan Road, Haidian District, Beijing 100191, China. zbmao@bjmu.edu.cn
Key Words Periodontitis; Periodontal ligament stem cells; Osteogenic differentiation; Circular RNA; MicroRNAs; Yes associated protein 1
Core Tip Periodontal ligament stem cells are promising candidate for the regenerative treatment of periodontal and alveolar bone tissues. Circular RNA ADP-ribosylation factor 3 was decreased in periodontal ligament tissues of periodontitis patients. Circular RNA ADP-ribosylation factor 3 promotes the osteogenic differentiation of periodontal ligament stem cells in periodontitis by acting as a sponge for miR-27b-3p and increasing the expression of its target gene, Yes associated protein 1. This suggests it could be a potential therapeutic target for regenerative treatment of periodontitis.
Publish Date 2026-06-25 08:21
Citation

Qi L, Wang XQ, Sun J, Li RZ, Mao ZB. Dysregulated circARF3/miR-27b-3p/YAP1 axis contributes to impaired osteogenic differentiation of periodontal ligament stem cells in periodontitis. World J Stem Cells 2026; 18(6): 116004

URL https://www.wjgnet.com/1948-0210/full/v18/i6/116004.htm
DOI https://doi.org/10.4252/wjsc.116004
Full Article (PDF) WJSC-18-116004-with-cover.pdf
Manuscript File 116004_Auto_Edited_071530.docx
Answering Reviewers 116004-answering-reviewers.pdf
Audio Core Tip 116004-audio.mp3
Biostatistics Review Certificate 116004-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116004-conflict-of-interest-statement.pdf
Copyright License Agreement 116004-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 116004-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116004-non-native-speakers.pdf
Peer-review Report 116004-peer-reviews.pdf
Scientific Misconduct Check 116004-scientific-misconduct-check.png
Scientific Editor Work List 116004-scientific-editor-work-list.pdf
CrossCheck Report 116004-crosscheck-report.pdf