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2/11/2026 7:19:24 AM | Browse: 2 | Download: 23
Publication Name World Journal of Gastroenterology
Manuscript ID 116016
Country China
Received
2025-10-31 06:47
Peer-Review Started
2025-10-31 06:47
First Decision by Editorial Office Director
2025-11-25 09:30
Return for Revision
2025-11-25 09:30
Revised
2025-12-06 09:34
Publication Fee Transferred
Second Decision by Editor
2025-12-24 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-24 10:23
Articles in Press
2025-12-24 10:23
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-04 09:13
Publish the Manuscript Online
2026-02-11 07:19
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Peroxiredoxin 1 as a novel pyroptosis inducer in colorectal cancer: Insights and future directions
Manuscript Source Unsolicited Manuscript
All Author List Zi-Ke Chen, Jia-Wei Zhao, Wen-Ying Meng and Yu-Gang Wang
ORCID
Author(s) ORCID Number
Yu-Gang Wang http://orcid.org/0000-0001-5675-2509
Funding Agency and Grant Number
Corresponding Author Yu-Gang Wang, Chief Physician, Department of Gastroenterology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Shanghai 200336, China. wang_yugang@sina.com
Key Words Colorectal cancer; Peroxiredoxin 1; Damage-associated molecular patterns; Pyroptosis; Gasdermin D
Core Tip Pyroptosis is a key link of “cell death-anti-tumor immunity” in colon cancer, which not only directly suppresses tumor through gasdermin D-mediated cell lysis, but also releases inflammatory factors to remodel the immune microenvironment. In the future, advancing targeted pyroptosis strategies toward molecular intervention, deepening mechanistic insights, and validating multi-dimensional approaches will be crucial to address current challenges and improve outcomes in colon cancer treatment.
Publish Date 2026-02-11 07:19
Citation

Chen ZK, Zhao JW, Meng WY, Wang YG. Peroxiredoxin 1 as a novel pyroptosis inducer in colorectal cancer: Insights and future directions. World J Gastroenterol 2026; 32(8): 116016

URL https://www.wjgnet.com/1007-9327/full/v32/i8/116016.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i8.116016
Full Article (PDF) WJG-32-116016-with-cover.pdf
Manuscript File 116016_Auto_Edited_071906.docx
Answering Reviewers 116016-answering-reviewers.pdf
Audio Core Tip 116016-audio.m4a
Conflict-of-Interest Disclosure Form 116016-conflict-of-interest-statement.pdf
Copyright License Agreement 116016-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116016-non-native-speakers.pdf
Peer-review Report 116016-peer-reviews.pdf
Scientific Misconduct Check 116016-scientific-misconduct-check.png
Scientific Editor Work List 116016-scientific-editor-work-list.pdf
CrossCheck Report 116016-crosscheck-report.pdf