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Articles Published Processes
4/15/2026 6:47:27 AM | Browse: 0 | Download: 0
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Received |
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2025-11-21 09:14 |
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Peer-Review Started |
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2025-11-21 09:14 |
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First Decision by Editorial Office Director |
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2025-12-16 06:31 |
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Return for Revision |
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2025-12-16 06:31 |
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Revised |
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2025-12-29 03:13 |
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Publication Fee Transferred |
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2025-12-31 09:13 |
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Second Decision by Editor |
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2026-02-04 02:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-04 08:05 |
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Articles in Press |
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2026-02-04 08:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-31 07:23 |
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Publish the Manuscript Online |
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2026-04-15 06:47 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Lymph node regression grade as a prognostic marker in rectal cancer after neoadjuvant therapy and radical resection
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yun-Jie Shi, Pan-Pan Duan, Qian-Qian Liu, Hong-Yan Ru, Ya-Jun Huang, Wen Xia, Ling Chen and Xu Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shanghai Municipal Health Commission |
20244Y0186 |
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| Corresponding Author |
Xu Li, Department of Colorectal Surgery, Changhai Hospital, The First Affiliated Hospital of Naval Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433, China. xuli_ch@163.com |
| Key Words |
Rectal cancer; Lymph node regression grade; Tumor regression grade; Neoadjuvant chemoradiotherapy; Prognostic marker |
| Core Tip |
In locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy, the prognostic value of the primary tumor regression grade is limited to patients without lymph node (LN) metastasis (ypN0). Importantly, we demonstrate that a novel LN regression grade, assessing residual cancer in treated LNs, serves as a powerful and independent prognostic marker for both survival and recurrence in patients with residual nodal disease (ypN+). Integrating LN regression grade into postoperative evaluation refines risk stratification beyond current tumor-node-metastasis staging. |
| Publish Date |
2026-04-15 06:47 |
| Citation |
Shi YJ, Duan PP, Liu QQ, Ru HY, Huang YJ, Xia W, Chen L, Li X. Lymph node regression grade as a prognostic marker in rectal cancer after neoadjuvant therapy and radical resection. World J Gastroenterol 2026; 32(15): 116026 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i15/116026.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i15.116026 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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