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5/20/2026 8:22:31 AM | Browse: 3 | Download: 18
Publication Name World Journal of Gastroenterology
Manuscript ID 116036
Country China
Received
2025-12-26 09:57
Peer-Review Started
2025-12-26 09:57
First Decision by Editorial Office Director
2026-01-12 08:21
Return for Revision
2026-01-12 08:21
Revised
2026-02-05 15:15
Publication Fee Transferred
2026-02-08 07:51
Second Decision by Editor
2026-03-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-04 04:42
Articles in Press
2026-03-04 04:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-13 00:41
Publish the Manuscript Online
2026-05-20 08:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Emergency Medicine
Manuscript Type Clinical Trials Study
Article Title Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis
Manuscript Source Unsolicited Manuscript
All Author List Lin-Gui Zhong, Yu Luo, Fang Gao, Ting-Ting Guo, Jian Yang and Chuan-Jiang Wang
ORCID
Author(s) ORCID Number
Jian Yang http://orcid.org/0000-0001-8170-0727
Chuan-Jiang Wang http://orcid.org/0000-0001-6620-3909
Funding Agency and Grant Number
Funding Agency Grant Number
Chongqing Science and Technology Foundation CSTB2025NSCQ-GPX1217
2024 Nursing Research Innovation Project of the First Affiliated Hospital of Chongqing Medical University HLPY2024-10
Natural Science Foundation of Tibet Autonomous Region XZ2024ZR-ZY100(Z)
Program for Youth Innovation in Future Medicine, Chongqing Medical University W0138
Chongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in the Three Gorges Reservoir Area Project KFKT2022009
Corresponding Author Chuan-Jiang Wang, PhD, Department of Emergency Medicine, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuanjiagang, Chongqing 400000, China. wangchuanjiang@cqmu.edu.cn
Key Words Acute pancreatitis; Rhubarb; T helper 17; Inflammation; Cytokines
Core Tip Acute pancreatitis (AP) is a disease with high mortality, caused by the activation of pancreatic enzymes due to multiple factors and characterized by localized pancreatic inflammation. Pharmacological studies indicate that rhubarb significantly improves intestinal blood perfusion, suppresses excessive inflammatory responses, modulates inflammatory mediator cascades, and enhances intestinal motility. However, whether rhubarb improves the prognosis and complications in patients with AP by inhibiting Th17 cell differentiation and inflammatory responses remains unclear. Therefore, this study was conducted to evaluate the role of rhubarb in patients with AP.
Publish Date 2026-05-20 08:22
Citation

Zhong LG, Luo Y, Gao F, Guo TT, Yang J, Wang CJ. Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis. World J Gastroenterol 2026; 32(20): 116036

URL https://www.wjgnet.com/1007-9327/full/v32/i20/116036.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i20.116036
Full Article (PDF) WJG-32-116036-with-cover.pdf
CONSORT 2010 Statement 116036-CONSORT-2010-statement.pdf
Manuscript File 116036_Auto_Edited_111102.docx
Answering Reviewers 116036-answering-reviewers.pdf
Audio Core Tip 116036-audio.mp3
Biostatistics Review Certificate 116036-biostatistics-statement.pdf
Clinical Trial Registration Statement 116036-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 116036-conflict-of-interest-statement.pdf
Copyright License Agreement 116036-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116036-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116036-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116036-non-native-speakers.pdf
Peer-review Report 116036-peer-reviews.pdf
Scientific Misconduct Check 116036-scientific-misconduct-check.png
Scientific Editor Work List 116036-scientific-editor-work-list.pdf
CrossCheck Report 116036-crosscheck-report.pdf