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Articles Published Processes
5/18/2026 8:33:18 AM | Browse: 0 | Download: 0
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Received |
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2025-11-02 12:28 |
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Peer-Review Started |
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2025-11-02 12:28 |
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First Decision by Editorial Office Director |
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2025-11-10 07:05 |
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Return for Revision |
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2025-11-10 07:05 |
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Revised |
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2025-11-26 05:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-10 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-10 10:05 |
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Articles in Press |
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2026-02-10 10:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-08 07:48 |
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Publish the Manuscript Online |
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2026-05-18 08:33 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Observational Study |
| Article Title |
Comparison of neurohormone and callus volume formation in long bone fractures associated with or without traumatic brain injury
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Prabu Mounisamy, Hrushikesh Singh, Balasubramaniyan Vairappan, Gopikrishnan Rajasekar, Sushma Chandrashekar, Naveen Jeyaraman and Madhan Jeyaraman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Madhan Jeyaraman, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nadu, India. madhanjeyaraman@gmail.com |
| Key Words |
Traumatic brain injury; Callus; Growth hormone; Interleukin; Parathyroid hormone; Long bone fractures |
| Core Tip |
Patients with traumatic brain injury (TBI) show enhanced fracture healing, potentially due to elevated systemic levels of growth hormone and parathyroid hormone. This prospective study reveals that growth hormone and parathyroid hormone positively correlate with increased callus volume, while interleukin-6 exhibits a variable role. Understanding these biochemical mediators may lead to novel therapeutic strategies that mimic TBI-associated osteogenesis to improve fracture outcomes in non-TBI patients. |
| Publish Date |
2026-05-18 08:33 |
| Citation |
Mounisamy P, Singh H, Vairappan B, Rajasekar G, Chandrashekar S, Jeyaraman N, Jeyaraman M. Comparison of neurohormone and callus volume formation in long bone fractures associated with or without traumatic brain injury. World J Orthop 2026; 17(5): 116068 |
| URL |
https://www.wjgnet.com/2218-5836/full/v17/i5/116068.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v17.i5.116068 |
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