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Articles Published Processes
7/24/2026 10:16:19 AM | Browse: 1 | Download: 0
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Received |
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2025-11-02 11:24 |
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Peer-Review Started |
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2025-11-02 11:24 |
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First Decision by Editorial Office Director |
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2025-11-06 09:01 |
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Return for Revision |
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2025-11-06 09:01 |
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Revised |
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2025-11-20 05:35 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-26 02:55 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-26 10:56 |
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Articles in Press |
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2026-01-26 10:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-11 04:29 |
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Publish the Manuscript Online |
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2026-07-24 10:16 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Cell source dictates the effect - a critical consideration for exosome-based cancer therapies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Feng-Juan Lyu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82272552 |
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| Corresponding Author |
Feng-Juan Lyu, Adjunct Associate Professor, Associate Professor, PhD, South China University of Technology-the University of Western Australia Joint Center for Regenerative Medicine Research, School of Medicine, South China University of Technology, Higher Education Mega Center, Panyu District, Guangzhou 510006, Guangdong Province, China. 44238553@qq.com |
| Key Words |
Exosome; Cell source; Cancer therapies; Mesenchymal stem cells; Induced pluripotent stem cells |
| Core Tip |
Building on the study by Ababneh et al, we emphasize that the anti-cancer effects of mesenchymal stem cells (MSCs) derived exosomes are profoundly source-dependent. The research demonstrates that exosomes from induced pluripotent stem cell-derived MSCs potently induce senescence in aggressive cancer cells, whereas those from bone marrow MSCs show weaker effects. This highlights the critical need to move beyond generic “MSCs-exosome” descriptions. We advocate for rigorous standardization and functional profiling of exosome sources to ensure reproducibility and clinical relevance in future therapies. |
| Publish Date |
2026-07-24 10:16 |
| Citation |
Lyu FJ. Letter to the Editor: Cell source dictates the effect - a critical consideration for exosome-based cancer therapies. World J Stem Cells 2026; 18(7): 116082
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i7/116082.htm |
| DOI |
https://doi.org/10.4252/wjsc.116082 |
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