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5/13/2026 8:18:32 AM | Browse: 6 | Download: 32
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 116098
Country Egypt
Received
2025-11-03 04:03
Peer-Review Started
2025-11-03 04:04
First Decision by Editorial Office Director
2025-12-09 09:26
Return for Revision
2025-12-09 09:26
Revised
2025-12-15 16:53
Publication Fee Transferred
Second Decision by Editor
2026-01-29 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-29 06:39
Articles in Press
2026-01-29 06:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-24 02:11
Publish the Manuscript Online
2026-05-13 08:18
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Observational Study
Article Title Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study
Manuscript Source Invited Manuscript
All Author List Esraa A Sorour, Eman M Elaskary, Shimaa Basyoni Elnemr, Adel A Hagag, Nesma Ahmed Kassab and Mohammed Al-Beltagi
ORCID
Author(s) ORCID Number
Esraa A Sorour http://orcid.org/0000-0003-0834-4070
Eman M Elaskary http://orcid.org/0009-0001-0321-1490
Shimaa Basyoni Elnemr http://orcid.org/0009-0003-7554-5566
Adel A Hagag http://orcid.org/0000-0002-7952-0089
Nesma Ahmed Kassab http://orcid.org/0009-0009-3576-8048
Mohammed Al-Beltagi http://orcid.org/0000-0002-7761-9536
Funding Agency and Grant Number
Corresponding Author Mohammed Al-Beltagi, Department of Pediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mohamed.elbeltagi@med.tanta.edu.eg
Key Words β-thalassemia major; Heart rate variability; Autonomic dysfunction; Pediatric cardiology; Iron overload
Core Tip Children with β-thalassemia major may develop cardiac dysfunction long before echocardiographic or clinical evidence appears. This study demonstrates that heart rate variability (HRV) analysis can detect early autonomic imbalance, reflecting subclinical cardiac involvement. Routine HRV monitoring in pediatric thalassemia patients offers a simple, non-invasive method to identify high-risk individuals and initiate preventive measures early, potentially improving cardiac outcomes and survival.
Publish Date 2026-05-13 08:18
Citation

Sorour EA, Elaskary EM, Elnemr SB, Hagag AA, Kassab NA, Al-Beltagi M. Evaluation of heart rate variability in pediatric patients with beta thalassemia major: Cross-sectional study. World J Clin Pediatr 2026; 15(2): 116098

URL https://www.wjgnet.com/2219-2808/full/v15/i2/116098.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i2.116098
Full Article (PDF) WJCP-15-116098-with-cover.pdf
STROBE Statement 116098-STROBE-statement.pdf
Manuscript File 116098_Auto_Edited-WJJ.docx
Answering Reviewers 116098-answering-reviewers.pdf
Audio Core Tip 116098-audio.mp3
Biostatistics Review Certificate 116098-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116098-conflict-of-interest-statement.pdf
Copyright License Agreement 116098-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116098-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116098-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116098-non-native-speakers.pdf
Peer-review Report 116098-peer-reviews.pdf
Scientific Misconduct Check 116098-scientific-misconduct-check.png
Scientific Editor Work List 116098-scientific-editor-work-list.pdf
CrossCheck Report 116098-crosscheck-report.pdf