BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/30/2026 7:49:03 AM | Browse: 1 | Download: 0
 |
Received |
|
2025-11-02 13:14 |
|
Peer-Review Started |
|
2025-11-02 13:14 |
|
First Decision by Editorial Office Director |
|
2025-12-02 07:05 |
|
Return for Revision |
|
2025-12-02 07:05 |
|
Revised |
|
2025-12-14 14:01 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-01-23 02:39 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-01-23 07:04 |
|
Articles in Press |
|
2026-01-23 07:04 |
|
Edit the Manuscript by Language Editor |
|
2026-01-30 11:41 |
|
Typeset the Manuscript |
|
2026-06-25 09:22 |
|
Publish the Manuscript Online |
|
2026-07-30 07:49 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Evaluation of the pathological cascade of post-subarachnoid hemorrhage anxiety and depression
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Teng-Fei Zeng, Jing-Yuan Zhang and Xue-Jian Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Program of Nantong City |
Key003, JCZ2022040 |
| Science and Technology Program of Nantong Health Committee |
MA2019003, MA2021017, MSZ2024038 |
| Kangda College of Nanjing Medical University |
KD2021JYYJYB025, KD2022KYJJZD022 |
| Kangda College of Nanjing Medical University |
KD2024KYJJ289, KD2025JYYJZD009 |
| Research Project on Teaching Reform of Nantong University |
2025J23 |
| Jiangsu Province Occupational Health Research Project |
JSZJ20251217 |
|
| Corresponding Author |
Xue-Jian Wang, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com |
| Key Words |
Subarachnoid hemorrhage; Anxiety; Depression; NOD-like receptor pyrin domain-containing 3 inflammasome; Diffusion tensor imaging; Limbic-prefrontal circuit |
| Core Tip |
This study revealed a novel pathological cascade of “cytotoxic edema - NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome activation - limbic-prefrontal circuit injury”, which is a key driver of anxiety and depression after subarachnoid hemorrhage. The contributions of this study are mainly reflected in three aspects: (1) Quantified the time-dependent changes of emotional behavior, brain structure, and inflammatory response, among which diffusion tensor imaging parameters and cerebrospinal fluid interleukin-1β can serve as objective indicators; (2) Confirmed that the NLRP3-interleukin-1β axis is a core regulatory node; and (3) Has translational value-diffusion tensor imaging can be used for risk stratification, and NLRP3 inhibitors can be used as intervention methods. |
| Publish Date |
2026-07-30 07:49 |
| Citation |
Zeng TF, Zhang JY, Wang XJ. Letter to the Editor: Evaluation of the pathological cascade of post-subarachnoid hemorrhage anxiety and depression. World J Psychiatry 2026; 16(8): 116117
|
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i8/116117.htm |
| DOI |
https://doi.org/10.5498/wjp.v16.i8.116117 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
