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3/27/2026 12:16:59 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 116149
Country China
Received
2025-11-18 09:27
Peer-Review Started
2025-11-18 09:27
First Decision by Editorial Office Director
2025-12-04 07:58
Return for Revision
2025-12-04 07:58
Revised
2025-12-10 15:07
Publication Fee Transferred
2025-12-13 02:53
Second Decision by Editor
2026-01-23 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-23 07:46
Articles in Press
2026-01-23 07:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-10 03:56
Publish the Manuscript Online
2026-03-27 12:16
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Influence of enhanced recovery after surgery protocol on first exhaust time after laparoscopic resection of colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Xiu-Lian Zhang, Qing-Qi Hong and You-Qing Huang
ORCID
Author(s) ORCID Number
You-Qing Huang http://orcid.org/0009-0002-9583-8123
Funding Agency and Grant Number
Corresponding Author You-Qing Huang, Department of Hepatobiliary, Pancreatic and Vascular Surgery, The First Affiliated Hospital of Xiamen University, No. 55 Zhenhai Road, Siming District, Xiamen 361003, Fujian Province, China. 13695002565@163.com
Key Words Enhanced recovery after surgery; Laparoscopic surgery; Colorectal cancer; Time to first flatus; Gastrointestinal function recovery
Core Tip Enhanced recovery after surgery (ERAS) may accelerate gastrointestinal recovery after laparoscopic colorectal cancer resection, but time-to-first-flatus is rarely treated as a time-to-event endpoint. In this single-center retrospective cohort (n = 80), an ERAS pathway emphasizing shortened fasting with preoperative carbohydrates, goal-directed fluid therapy, multimodal analgesia, early mobilization, and early enteral nutrition was associated with a markedly earlier first flatus (approximately 1.3 days sooner), faster first defecation and bowel-sound recovery, fewer gastrointestinal symptoms, shorter length of stay (approximately 3.2 days reduction), and fewer complications. Analyses should prioritize survival methods (Kaplan-Meier, Cox/accelerated failure time) and adjust for secular trends and confounding (e.g., calendar month, operative factors, opioid use), with propensity techniques as sensitivity checks. Findings support routine ERAS implementation and adherence monitoring to improve postoperative intestinal function and hospitalization metrics, while acknowledging single-center, time-segmented design limitations.
Publish Date 2026-03-27 12:16
Citation

Zhang XL, Hong QQ, Huang YQ. Influence of enhanced recovery after surgery protocol on first exhaust time after laparoscopic resection of colorectal cancer. World J Gastrointest Surg 2026; 18(3): 116149

URL https://www.wjgnet.com/1948-9366/full/v18/i3/116149.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i3.116149
Full Article (PDF) WJGS-18-116149-with-cover.pdf
Manuscript File 116149_Auto_Edited_093737.docx
Answering Reviewers 116149-answering-reviewers.pdf
Audio Core Tip 116149-audio.mp3
Biostatistics Review Certificate 116149-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116149-conflict-of-interest-statement.pdf
Copyright License Agreement 116149-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116149-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116149-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116149-non-native-speakers.pdf
Peer-review Report 116149-peer-reviews.pdf
Scientific Misconduct Check 116149-scientific-misconduct-check.png
Scientific Editor Work List 116149-scientific-editor-work-list.pdf
CrossCheck Report 116149-crosscheck-report.pdf