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Articles Published Processes
3/30/2026 8:58:30 AM | Browse: 0 | Download: 0
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Received |
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2025-11-21 09:18 |
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Peer-Review Started |
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2025-11-21 09:18 |
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First Decision by Editorial Office Director |
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2025-12-11 07:44 |
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Return for Revision |
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2025-12-11 07:44 |
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Revised |
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2025-12-20 13:08 |
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Publication Fee Transferred |
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2025-12-23 17:04 |
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Second Decision by Editor |
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2026-01-12 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-12 08:24 |
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Articles in Press |
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2026-01-12 08:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-18 10:57 |
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Publish the Manuscript Online |
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2026-03-30 08:58 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Prospective Study |
| Article Title |
Anxiety, depression, and quality of life in hepatocellular carcinoma treated with drug-eluting microspheres plus lenvatinib: A prospective study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Yu Liu, Zhi-Hui Liang, Jing-Lei Liu, Liang Li, Bao Cui and Tie-Gang Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| 2023 Hebei Provincial Medical Scientific Research Project Plan |
20231304 |
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| Corresponding Author |
Jian-Yu Liu, Department of Interventional Treatment, Bethune International Peace Hospital of PLA, No. 398 Zhongshan West Road, Qiaoxi District, Shijiazhuang 050082, Hebei Province, China. ljiany109527@163.com |
| Key Words |
Anxiety; Depression; Drug-eluting microspheres; Hepatocellular carcinoma; Lenvatinib; Quality of life |
| Core Tip |
This study investigated the impact of drug-eluting microsphere - transcatheter arterial chemoembolization (DEM-TACE) combined with lenvatinib on anxiety, depression, and quality of life (QoL) in patients with hepatocellular carcinoma (HCC). Among 126 enrolled patients, the prevalence of anxiety and depression significantly decreased over 12 months, accompanied by marked improvements in global health and functional scores on European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 and Quality of Life Questionnaire-Hepatocellular Carcinoma 18. The combination therapy showed favorable tumor response and manageable toxicity. These findings highlight the dual benefits of DEM-TACE plus lenvatinib in improving both psychological well-being and overall QoL in HCC management. |
| Publish Date |
2026-03-30 08:58 |
| Citation |
Liu JY, Liang ZH, Liu JL, Li L, Cui B, Li TG. Anxiety, depression, and quality of life in hepatocellular carcinoma treated with drug-eluting microspheres plus lenvatinib: A prospective study. World J Psychiatry 2026; 16(4): 116158 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i4/116158.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i4.116158 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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