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7/10/2026 10:11:23 AM | Browse: 1 | Download: 0
Publication Name World Journal of Methodology
Manuscript ID 116174
Country Brazil
Received
2025-11-04 04:29
Peer-Review Started
2025-11-04 04:29
First Decision by Editorial Office Director
2025-11-14 07:58
Return for Revision
2025-11-14 07:58
Revised
2025-12-08 02:13
Publication Fee Transferred
Second Decision by Editor
2026-02-09 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-09 07:39
Articles in Press
2026-02-09 07:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-31 03:49
Publish the Manuscript Online
2026-07-10 10:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Efficacy of duodenoscope with disposable distal cap in reducing microbial contamination: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Beanie Conceição Medeiros Nunes, Stefano Baraldo, Joao Ricardo Duda, Luiza Fenelon, Matheus Cavalcante Franco, Murilo Cavalcante Netto do Carmo, Diogo Bergesch Diedrich, Marcelo Cristalli Pacheco da Costa and Angelo So Taa Kum
ORCID
Author(s) ORCID Number
Beanie Conceição Medeiros Nunes http://orcid.org/0000-0001-6182-1644
Stefano Baraldo http://orcid.org/0000-0002-6359-9167
Joao Ricardo Duda http://orcid.org/0009-0008-1514-0811
Luiza Fenelon http://orcid.org/0009-0008-9336-0051
Matheus Cavalcante Franco http://orcid.org/0000-0003-0525-8003
Murilo Cavalcante Netto do Carmo http://orcid.org/0009-0001-4110-5613
Diogo Bergesch Diedrich http://orcid.org/0009-0008-9742-4972
Marcelo Cristalli Pacheco da Costa http://orcid.org/0009-0000-3280-5063
Angelo So Taa Kum http://orcid.org/0000-0003-2626-8235
Funding Agency and Grant Number
Corresponding Author Angelo So Taa Kum, MD, Senior Researcher, Department of Gastroenterology Endoscopy Unit, Hospital das Clínicas, Faculty of Medicine, University of Sao Paulo, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, Sao Paulo 05403-010, SP, Brazil. angelo.kum@alumni.usp.br
Key Words Duodenoscope with disposable distal cap; Standard duodenoscope; High-level disinfection; Microbial contamination; Systematic review; Meta-analysis
Core Tip This systematic review and meta-analysis synthesize data from four randomized controlled trials, providing high-quality evidence that disposable distal caps are a highly effective solution to duodenoscope contamination. The primary finding demonstrates a 68% relative risk reduction in microbial contamination, as measured by adenosine triphosphate levels, following high-level disinfection when compared to standard duodenoscopes. This study strongly supports the adoption of disposable distal caps technology as a critical engineering control to enhance reprocessing safety and mitigate the transmission of healthcare-associated infections.
Publish Date 2026-07-10 10:11
Citation

Nunes BCM, Baraldo S, Duda JR, Fenelon L, Franco MC, do Carmo MCN, Diedrich DB, da Costa MCP, Kum AST. Efficacy of duodenoscope with disposable distal cap in reducing microbial contamination: A systematic review and meta-analysis. World J Methodol 2026; 16(3): 116174

URL https://www.wjgnet.com/2222-0682/full/v16/i3/116174.htm
DOI https://doi.org/10.5662/wjm.116174
Full Article (PDF) WJM-16-116174-with-cover.pdf
PRISMA 2009 Checklist 116174-PRISMA-2009-Checklist.pdf
Manuscript File 116174_Auto_Edited-WJJ.docx
Answering Reviewers 116174-answering-reviewers.pdf
Audio Core Tip 116174-audio.m4a
Biostatistics Review Certificate 116174-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116174-conflict-of-interest-statement.pdf
Copyright License Agreement 116174-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116174-non-native-speakers.pdf
Peer-review Report 116174-peer-reviews.pdf
Scientific Misconduct Check 116174-scientific-misconduct-check.png
Scientific Editor Work List 116174-scientific-editor-work-list.pdf
CrossCheck Report 116174-crosscheck-report.pdf