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7/30/2026 7:49:09 AM | Browse: 0 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 116190
Country India
Received
2025-11-04 14:57
Peer-Review Started
2025-11-04 14:57
First Decision by Editorial Office Director
2025-12-09 07:02
Return for Revision
2025-12-09 07:02
Revised
2025-12-18 09:53
Publication Fee Transferred
Second Decision by Editor
2026-01-26 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-26 06:17
Articles in Press
2026-01-26 06:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-16 09:55
Publish the Manuscript Online
2026-07-30 07:49
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Correspondence
Article Title Letter to the Editor: Adolescent mental health in transition - bridging neurobiological insights and modifiable risk factors for anxiety and depression
Manuscript Source Invited Manuscript
All Author List Devlina Ghosh
ORCID
Author(s) ORCID Number
Devlina Ghosh http://orcid.org/0000-0003-1167-6009
Funding Agency and Grant Number
Corresponding Author Devlina Ghosh, Assistant Professor, PhD, Department of Biochemistry, Saraswati Dental College and Hospital, 233 Tiwariganj, Ayodhya Road, Lucknow 226028, Uttar Pradesh, India. ghoshdevlin6@gmail.com
Key Words Adolescents; Functional constipation; Anxiety; Depression; Brain-gut axis; Neuropsychiatry; Neuroinflammation; Neuroplasticity
Core Tip Yang et al’s large adolescent cohort suggests that functional constipation reflects gut-brain axis disruption associated with increased anxiety and depression risk. This letter integrates emerging evidence indicating that gut dysbiosis, altered microbial metabolites, systemic inflammation, microglial activation, and reduced brain-derived neurotrophic factor-mediated neuroplasticity converge on mood regulation. It further underscores the need for longitudinal, biomarker-informed studies and scalable school-based interventions targeting diet, lifestyle, and microbiome-modulating strategies to enable precision prevention in youth mental health.
Publish Date 2026-07-30 07:49
Citation

Ghosh D. Letter to the Editor: Adolescent mental health in transition - bridging neurobiological insights and modifiable risk factors for anxiety and depression. World J Psychiatry 2026; 16(8): 116190

URL https://www.wjgnet.com/2220-3206/full/v16/i8/116190.htm
DOI https://doi.org/10.5498/wjp.v16.i8.116190
Full Article (PDF) WJP-16-116190-with-cover.pdf
Manuscript File 116190_Auto_Edited_003853.docx
Answering Reviewers 116190-answering-reviewers.pdf
Audio Core Tip 116190-audio.mp3
Conflict-of-Interest Disclosure Form 116190-conflict-of-interest-statement.pdf
Copyright License Agreement 116190-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116190-non-native-speakers.pdf
Supplementary Material 116190-supplementary-material.pdf
Peer-review Report 116190-peer-reviews.pdf
Scientific Misconduct Check 116190-scientific-misconduct-check.png
Scientific Editor Work List 116190-scientific-editor-work-list.pdf
CrossCheck Report 116190-crosscheck-report.pdf