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Articles Published Processes
3/25/2026 8:45:03 AM | Browse: 10 | Download: 36
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Received |
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2025-11-06 06:57 |
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Peer-Review Started |
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2025-11-06 06:57 |
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First Decision by Editorial Office Director |
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2025-12-09 07:20 |
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Return for Revision |
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2025-12-09 07:20 |
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Revised |
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2025-12-12 18:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-29 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-05 10:54 |
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Articles in Press |
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2026-02-05 10:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-28 10:09 |
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Publish the Manuscript Online |
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2026-03-25 08:45 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mahmood S Choudhery, Taqdees Arif, Ruhma Mahmood and David T Harris |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mahmood S Choudhery, Associate Professor, Department of Human Genetics and Molecular Biology, University of Health Sciences, Khayaban-e-Jamia Punjab, Lahore 54000, Punjab, Pakistan. ms20031@yahoo.com |
| Key Words |
Neurodegenerative diseases; Alzheimer’s disease; Parkinson’s disease; Stroke; Exosomes; Acellular therapy |
| Core Tip |
Neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis, are progressive and irreversible conditions marked by neuronal loss, misfolded protein accumulation, and severe cognitive or motor decline. Current therapies cannot halt neuronal death, and stem cell transplantation is limited by the blood-brain barrier. Exosomes, nanoscale vesicles secreted by cells, overcome this limitation by naturally crossing the blood-brain barrier, carrying proteins, nucleic acids, and lipids with neuroprotective potential. Their role in diagnosis, biomarker discovery, and targeted drug delivery highlights exosomes as promising acellular therapeutics for neurodegenerative disorders, with growing clinical interest and translational potential. |
| Publish Date |
2026-03-25 08:45 |
| Citation |
Choudhery MS, Arif T, Mahmood R, Harris DT. Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders. World J Stem Cells 2026; 18(3): 116226 |
| URL |
https://www.wjgnet.com/1948-0210/full/v18/i3/116226.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i3.116226 |
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