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3/25/2026 8:45:03 AM | Browse: 10 | Download: 36
Publication Name World Journal of Stem Cells
Manuscript ID 116226
Country Pakistan
Received
2025-11-06 06:57
Peer-Review Started
2025-11-06 06:57
First Decision by Editorial Office Director
2025-12-09 07:20
Return for Revision
2025-12-09 07:20
Revised
2025-12-12 18:00
Publication Fee Transferred
Second Decision by Editor
2026-01-29 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-05 10:54
Articles in Press
2026-02-05 10:54
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 10:09
Publish the Manuscript Online
2026-03-25 08:45
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders
Manuscript Source Invited Manuscript
All Author List Mahmood S Choudhery, Taqdees Arif, Ruhma Mahmood and David T Harris
ORCID
Author(s) ORCID Number
Mahmood S Choudhery http://orcid.org/0000-0003-2038-4817
Taqdees Arif http://orcid.org/0000-0002-0258-1510
Ruhma Mahmood http://orcid.org/0000-0001-8548-7927
Funding Agency and Grant Number
Corresponding Author Mahmood S Choudhery, Associate Professor, Department of Human Genetics and Molecular Biology, University of Health Sciences, Khayaban-e-Jamia Punjab, Lahore 54000, Punjab, Pakistan. ms20031@yahoo.com
Key Words Neurodegenerative diseases; Alzheimer’s disease; Parkinson’s disease; Stroke; Exosomes; Acellular therapy
Core Tip Neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis, are progressive and irreversible conditions marked by neuronal loss, misfolded protein accumulation, and severe cognitive or motor decline. Current therapies cannot halt neuronal death, and stem cell transplantation is limited by the blood-brain barrier. Exosomes, nanoscale vesicles secreted by cells, overcome this limitation by naturally crossing the blood-brain barrier, carrying proteins, nucleic acids, and lipids with neuroprotective potential. Their role in diagnosis, biomarker discovery, and targeted drug delivery highlights exosomes as promising acellular therapeutics for neurodegenerative disorders, with growing clinical interest and translational potential.
Publish Date 2026-03-25 08:45
Citation

Choudhery MS, Arif T, Mahmood R, Harris DT. Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders. World J Stem Cells 2026; 18(3): 116226

URL https://www.wjgnet.com/1948-0210/full/v18/i3/116226.htm
DOI https://dx.doi.org/10.4252/wjsc.v18.i3.116226
Full Article (PDF) WJSC-18-116226-with-cover.pdf
Manuscript File 116226_Auto_Edited_081555.docx
Answering Reviewers 116226-answering-reviewers.pdf
Audio Core Tip 116226-audio.ogg
Conflict-of-Interest Disclosure Form 116226-conflict-of-interest-statement.pdf
Copyright License Agreement 116226-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116226-non-native-speakers.pdf
Peer-review Report 116226-peer-reviews.pdf
Scientific Misconduct Check 116226-scientific-misconduct-check.png
Scientific Editor Work List 116226-scientific-editor-work-list.pdf
CrossCheck Report 116226-crosscheck-report.pdf