Publication Name	World Journal of Transplantation
Manuscript ID	11624
Country	United Kingdom

Received	2014-05-28 20:05
Peer-Review Started	2014-05-28 22:41
To Make the First Decision	2014-06-27 11:52
Return for Revision	2014-06-27 18:55
Revised	2014-07-08 17:04
Second Decision	2014-11-03 16:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-11-03 17:10
Articles in Press	2014-11-03 17:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-15 16:32
Publish the Manuscript Online	2014-12-29 17:46

ISSN	2220-3230 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Autobiography
Article Title	1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor
Manuscript Source	Invited Manuscript
All Author List	Sarah A Hosgood, Phillip J Yates and Michael L Nicholson
Funding Agency and Grant Number
Corresponding Author	Dr. Sarah A Hosgood, Department of Infection, Immunity and Inflammation, Transplant Group.University of Leicester, Gwendolen Road, LE5 4PW Leicester, United Kingdom. sarahhosgood@hotmail.com
Key Words	Kidney; Transplantation; Ischemia; Donation after circulatory death; Inducible nitric oxide
Core Tip	It is important to examine the effects of therapies that can reduce ischaemia reperfusion injury particularly in donation after circulatory death donor kidneys. The biological role of inducible nitric oxide synthase (iNOS) is somewhat controversial. This study uses a large animal ex vivo model to assess the effects of 1400W, an iNOS inhibitor. The model provides a functional assessment of each kidney, providing a close simulation to clinical transplantation. The study found that 1400W improved early renal function and oxidative stress.
Publish Date	2014-12-29 17:46
Citation	Hosgood SA, Yates PJ, Nicholson ML. 1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor. World J Transplant 2014; 4(4): 299-305
URL	http://www.wjgnet.com/2220-3230/full/v4/i4/299.htm
DOI	http://dx.doi.org/10.5500/wjt.v4.i4.299

Full Article (PDF)	WJT-4-299.pdf
Full Article (Word)	WJT-4-299.doc
Manuscript File	11624-Review.doc
Answering Reviewers	11624-Answering Reviewers.pdf
Copyright License Agreement	11624-Copyright assignment.pdf
Peer-review Report	11624-Peer Review.pdf
Scientific Misconduct Check	11624-CrossCheck.jpg
Scientific Editor Work List	11624-Scientific editor work list.pdf