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Publication Name World Journal of Clinical Oncology
Manuscript ID 116251
Country Kyrgyzstan
Received
2025-11-06 14:01
Peer-Review Started
2025-11-06 14:01
First Decision by Editorial Office Director
2025-12-09 07:21
Return for Revision
2025-12-09 08:17
Revised
2025-12-11 20:33
Publication Fee Transferred
Second Decision by Editor
2026-01-14 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-14 08:28
Articles in Press
2026-01-14 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-26 10:31
Publish the Manuscript Online
2026-02-06 06:30
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Cancer stem cell markers, chemotherapy response, and survival in triple-negative breast cancer
Manuscript Source Unsolicited Manuscript
All Author List Faisal Nabi Depar, Ahmed Jamal Chaudhary, Jawad Hameed, Faisal Sarwar Abbasi, BiBi Uzma, Amjad Ali, Naheed Akhtar, Rizwan Khan, Afsheen Siddiqi and Sohail Riaz
ORCID
Author(s) ORCID Number
Faisal Nabi Depar http://orcid.org/0009-0004-0019-8819
Ahmed Jamal Chaudhary http://orcid.org/0000-0001-6126-4139
Naheed Akhtar http://orcid.org/0000-0002-5901-7304
Rizwan Khan http://orcid.org/0000-0001-6745-0733
Sohail Riaz http://orcid.org/0009-0006-4406-1691
Funding Agency and Grant Number
Corresponding Author Sohail Riaz, MD, Department of Medicine, International University of Kyrgyzstan, International School of Medicine, 6 Seven April Street, Bishkek 720054, Kyrgyzstan. sohailriaz552@gmail.com
Key Words Triple-negative breast cancer; Cancer stem cells; CD44; CD24; Aldehyde dehydrogenase 1; Chemotherapy response; Survival; Pakistan
Core Tip In a Pakistani triple-negative breast cancer cohort, the cancer stem cell phenotype (CD44 high/CD24 low/aldehyde dehydrogenase 1 positive) occurred in 10.2% of cases and independently predicted markedly lower pathological complete response (5.0% vs 51.8%) and shorter overall survival (hazard ratio = 4.35). These findings from a South Asian population with high triple-negative breast cancer burden support cancer stem cell marker integration into risk stratification for personalized therapy in resource-limited settings.
Publish Date 2026-02-06 06:30
Citation

Depar FN, Chaudhary AJ, Hameed J, Abbasi FS, Uzma B, Ali A, Akhtar N, Khan R, Siddiqi A, Riaz S. Cancer stem cell markers, chemotherapy response, and survival in triple-negative breast cancer. World J Clin Oncol 2026; 17(2): 116251

URL https://www.wjgnet.com/2218-4333/full/v17/i2/116251.htm
DOI https://dx.doi.org/10.5306/wjco.v17.i2.116251
Full Article (PDF) WJCO-17-116251-with-cover.pdf
STROBE Statement 116251-STROBE-statement.pdf
Manuscript File 116251_Auto_Edited_101039.docx
Answering Reviewers 116251-answering-reviewers.pdf
Audio Core Tip 116251-audio.mp3
Biostatistics Review Certificate 116251-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116251-conflict-of-interest-statement.pdf
Copyright License Agreement 116251-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116251-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116251-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116251-non-native-speakers.pdf
Supplementary Material 116251-supplementary-material.pdf
Peer-review Report 116251-peer-reviews.pdf
Scientific Misconduct Check 116251-scientific-misconduct-check.png
Scientific Editor Work List 116251-scientific-editor-work-list.pdf
CrossCheck Report 116251-crosscheck-report.pdf