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Articles Published Processes
3/15/2026 6:19:15 AM | Browse: 6 | Download: 29
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Received |
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2025-11-10 15:15 |
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Peer-Review Started |
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2025-11-10 15:17 |
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First Decision by Editorial Office Director |
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2025-12-24 10:11 |
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Return for Revision |
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2025-12-24 10:11 |
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Revised |
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2026-01-06 15:01 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-14 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-14 07:30 |
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Articles in Press |
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2026-02-14 07:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-04 02:06 |
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Publish the Manuscript Online |
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2026-03-15 06:19 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ajay Kodiyatar, Akhilesh Mishra, Megh Singh Dhakad, Vandana Roy, Mirza Masroor Ali Beg and Niket Rai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Niket Rai, MD, PhD, Professor, Department of Pharmacology, L N Medical College, Sarvadharam C-Sector, Kolar Road, Bhopal 462042, Madhya Pradesh, India. rainiket26@gmail.com |
| Key Words |
Gymnema sylvestre; Metformin; Type 2 diabetes mellitus; Insulin resistance; Combination therapy |
| Core Tip |
This study evaluates the antidiabetic effects of Gymnema sylvestre (GS) alone and in combination with metformin in a high-fat diet and streptozotocin-induced type 2 diabetic rat model. The combination therapy improved glycemic control, lipid profile, renal parameters, and body weight compared with GS alone, although metformin remained superior. These findings support the potential role of GS as an adjunct to standard metformin therapy in type 2 diabetes mellitus. |
| Publish Date |
2026-03-15 06:19 |
| Citation |
Kodiyatar A, Mishra A, Dhakad MS, Roy V, Beg MMA, Rai N. Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model. World J Exp Med 2026; 16(1): 116252 |
| URL |
https://www.wjgnet.com/2220-315x/full/v16/i1/116252.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v16.i1.116252 |
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