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12/2/2014 10:47:00 AM | Browse: 1268 | Download: 1198
Publication Name World Journal of Gastroenterology
Manuscript ID 11627
Country/Territory Italy
Received
2014-05-28 21:18
Peer-Review Started
2014-05-29 00:29
To Make the First Decision
2014-07-09 12:10
Return for Revision
2014-07-17 15:17
Revised
2014-08-08 06:03
Second Decision
2014-09-30 09:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-09-30 10:08
Articles in Press
2014-09-30 10:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-10-04 04:33
Typeset the Manuscript
2014-11-15 18:16
Publish the Manuscript Online
2014-12-02 10:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease
Manuscript Source Invited Manuscript
All Author List Sara Ceccarelli, Valerio Nobili and Anna Alisi
Funding Agency and Grant Number
Funding Agency Grant Number
Associazione Italiana per la Ricerca sul Cancro (AIRC) MFAG 12936 (to Anna Alisi)
Corresponding Author Anna Alisi, PhD, Hepato-Metabolic Disease Unit and Liver Research Unit, Bambino Gesù Children’s Hospital, IRCCS, S. Onofrio Square 4, 00165 Rome, Italy. anna.alisi@opbg.net
Key Words Alcoholic liver disease; Toll-like receptors; Inflammation; Cirrhosis; Nuclear factor-B; Cytokines
Core Tip Alcoholic liver disease (ALD) pathogenesis is quite complex and requires the activation/inhibition of several molecular pathways. The inflammatory storm caused by alcohol abuse on the gut-liver axis and consequent activation of Toll-like receptor (TLR) signaling is topical for researchers and physicians, both for understanding ALD pathophysiology and for translating novel clues into clinical practice. Here, we focus on the current evidence of TLR involvement in inflammation during ALD in experimental models and humans, offering readers with no first-hand knowledge of this topic a valuable tool to start novel studies.
Publish Date 2014-12-02 10:46
Citation Ceccarelli S, Nobili V, Alisi A. Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease. World J Gastroenterol 2014; 20(44): 16443-16451
URL http://www.wjgnet.com/1007-9327/full/v20/i44/16443.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i44.16443
Full Article (PDF) WJG-20-16443.pdf
Full Article (Word) WJG-20-16443.doc
Manuscript File 11627-Review.doc
Answering Reviewers 11627-Answering reviewers.pdf
Copyright License Agreement 11627-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 11627-Language certificate.pdf
Peer-review Report 11627-Peer review(s).pdf
Scientific Misconduct Check 11627-CrossCheck.jpg
Scientific Editor Work List 11627-Scientific editor work list.pdf