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10/10/2026 9:09:42 AM | Browse: 1 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 116333
Country China
Received
2025-11-10 04:26
Peer-Review Started
2025-11-10 04:26
First Decision by Editorial Office Director
2025-11-24 11:58
Return for Revision
2025-11-24 11:58
Revised
2025-12-23 10:13
Publication Fee Transferred
Second Decision by Editor
2026-01-14 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-14 05:58
Articles in Press
2026-01-14 05:58
Edit the Manuscript by Language Editor
2026-01-19 16:57
Typeset the Manuscript
2026-07-01 08:03
Publish the Manuscript Online
2026-10-10 09:09
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Opinion Review
Article Title Guanxinning for antipsychotic-induced cardiotoxicity: A critical appraisal of emerging evidence
Manuscript Source Invited Manuscript
All Author List Yang Cao, Peng-Fei Li, Lin Zhu, Ke Li, Xu-Dong Duan, Yu-Fei Bao, Hong-Jun Sun and Kuan-Jun He
ORCID
Author(s) ORCID Number
Kuan-Jun He http://orcid.org/0009-0005-4220-7186
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Inner Mongolia Autonomous Region 2024LHMS08003
Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of Inner Mongolia Academy of Medical Sciences 2024GLLH0844
Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of Inner Mongolia Academy of Medical Sciences 2024GLLH0943
Corresponding Author Kuan-Jun He, PhD, Professor, College of Life Sciences and Food Engineering, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Tongliao 028000, Inner Mongolia Autonomous Region, China. hekuanjun@imun.edu.cn
Key Words Guanxinning; Antipsychotic drugs; Cardiac function; Protective role; Clinical implications
Core Tip Guanxinning may have a certain effect on improving cardiotoxicity caused by antipsychotics. Some trials have found that long-term use of antipsychotics can affect cardiac electrophysiology, myocardial function and biomarkers. However, these findings are based on surrogate indicators and the study subjects have no prior cardiovascular disease, so their limitations are relatively large. Current evidence is not sufficient to support routine use, and its benefits are still in the preliminary stage. Larger-scale studies targeting high-risk populations and observing cardiovascular disease outcomes are needed to clarify the effect.
Publish Date 2026-10-10 09:09
Citation

Cao Y, Li PF, Zhu L, Li K, Duan XD, Bao YF, Sun HJ, He KJ. Guanxinning for antipsychotic-induced cardiotoxicity: A critical appraisal of emerging evidence. World J Psychiatry 2026; 16(10): 116333

URL https://www.wjgnet.com/2220-3206/full/v16/i10/116333.htm
DOI https://doi.org/10.5498/wjp.116333
Full Article (PDF) WJP-16-116333-with-cover.pdf
Manuscript File 116333_Auto_Edited_021509.docx
Answering Reviewers 116333-answering-reviewers.pdf
Audio Core Tip 116333-audio.mp3
Conflict-of-Interest Disclosure Form 116333-conflict-of-interest-statement.pdf
Copyright License Agreement 116333-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116333-non-native-speakers.pdf
Peer-review Report 116333-peer-reviews.pdf
Scientific Misconduct Check 116333-scientific-misconduct-check.png
CrossCheck Report 116333-crosscheck-report.pdf