| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Detection rate and risk factors of colorectal adenoma in high-altitude population: A cross-sectional study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Lei Zhao, Wang-Yang Chen, Yi-Meng Liu, Suo-Lang Danzeng, Qu-Zhen Pingcuo, Zhen Yu, Hong-Da Chen, Yang-Jin Ciren and Dong Wu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Scientific Research Development Funds of Peking University People’s Hospital |
RDJP2022-15 |
| the Xizang Autonomous Region Natural Science Foundation Group Medical Aid Project |
XZ2024ZR-ZY012(Z) |
| Clinical Research Excellence Program for Research-Oriented Wards |
BRWEP2024W034010103 |
| Science and Technology Projects of Xizang Autonomous Region, China |
XZ202501JD0021 |
| Science and Technology Projects of Xizang Autonomous Region, China |
XZ202501ZY0072 |
| National Key Research and Development Program of China |
2024YFA0918504 |
| Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences |
2022-I2M-1-003 |
|
| Corresponding Author |
Dong Wu, Chief Physician, PhD, President, Professor, Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, Beijing, China. wudong@pumch.cn |
| Key Words |
High altitude; Xizang Autonomous Region; Colorectal adenoma; Colorectal cancer; Detection rate |
| Core Tip |
In this cross-sectional study of 1154 Tibetans, the colorectal adenoma (CRA) detection rate in the high-altitude Xizang Autonomous Region population was 7.7%. This was significantly lower than the 22.8% rate found in a rigorously matched low-altitude Beijing cohort. Advanced age and male sex were identified as the only independent risk factors for CRA in the Xizang Autonomous Region group. |
| Publish Date |
2026-02-03 06:28 |
| Citation |
Zhao XL, Chen WY, Liu YM, Danzeng SL, Pingcuo QZ, Yu Z, Chen HD, Ciren YJ, Wu D. Detection rate and risk factors of colorectal adenoma in high-altitude population: A cross-sectional study. World J Gastrointest Oncol 2026; 18(2): 116336 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i2/116336.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i2.116336 |
