Publication Name	World Journal of Ophthalmology
Manuscript ID	11635
Country	United States

Received	2014-05-29 09:52
Peer-Review Started	2014-05-29 22:36
To Make the First Decision	2014-07-29 12:01
Return for Revision	2014-07-30 10:26
Revised	2014-09-07 00:00
Second Decision	2014-10-27 16:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-10-27 17:02
Articles in Press	2014-10-27 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-04 16:41
Publish the Manuscript Online	2014-11-14 13:11

ISSN	2218-6239 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Ophthalmology
Manuscript Type	Minireviews
Article Title	Age-related macular degeneration treatment in the era of molecular medicine
Manuscript Source	Invited Manuscript
All Author List	Rick N Nordgren, Ahmed M Elkeeb and Bernard F Godley
Funding Agency and Grant Number
Corresponding Author	Bernard F Godley, MD, PhD, MBA, FACS, Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas 77555, United States. bgodley@utmb.edu
Key Words	Age-related macular degeneration; Stem cell therapy; Anti-vascular endothelial growth factor; Gene therapy; Complement factor H; High-temperature requirement factor A1; Age-relateed maculopathy susceptibility 2; Pharmacogenomics; Genetics
Core Tip	New therapies for age-related macular degeneration (AMD) such as stem cell transplantation and viral vector delivery are currently under intense investigation. Possible new treatments for both non-exudative and exudative AMD are on the horizon. Human embryonic stem cell derived retinal pigment epithelial cells have been transplanted into the subretinal space in human subjects. Viral vectors that encode proteins with a strong affinity for vascular endothelial growth factor are in clinical trials. In light of these exciting advances in both genetic and stem cell therapy, the future of AMD treatment shows substantial promise.
Publish Date	2014-11-14 13:11
Citation	Nordgren RN, Elkeeb AM, Godley BF. Age-related macular degeneration treatment in the era of molecular medicine. World J Ophthalmol 2014; 4(4): 130-139
URL	http://www.wjgnet.com/2218-6239/full/v4/i4/130.htm
DOI	http://dx.doi.org/10.5318/wjo.v4.i4.130

Full Article (PDF)	WJO-4-130.pdf
Full Article (Word)	WJO-4-130.doc
Manuscript File	11635-Review.docx
Answering Reviewers	11635-Answering reviewers.pdf
Copyright License Agreement	11635-Copyright assignment.pdf
Peer-review Report	11635-Peer review(s).pdf
Scientific Misconduct Check	11635-CrossCheck.jpg
Scientific Editor Work List	11635-Scientific editor work list.pdf