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Articles Published Processes
1/16/2026 11:31:16 AM | Browse: 66 | Download: 195
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Received |
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2025-11-10 05:36 |
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Peer-Review Started |
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2025-11-10 05:36 |
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First Decision by Editorial Office Director |
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2025-11-18 11:17 |
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Return for Revision |
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2025-11-18 11:17 |
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Revised |
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2025-11-18 17:01 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-08 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-08 07:55 |
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Articles in Press |
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2025-12-08 07:55 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-06 01:05 |
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Publish the Manuscript Online |
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2026-01-16 11:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Minireviews |
| Article Title |
Misdiagnosis of alpha-gal syndrome as non-celiac gluten sensitivity or lactose intolerance: A diagnostic blind spot for clinicians
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ayoola Awosika and Prithvi Balaji |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ayoola Awosika, MD, Department of Family Medicine, University of Illinois College of Medicine Peoria, 1 Illini Drive, Bloomington, IL 61601, United States. ayoolaawosika@yahoo.com |
| Key Words |
Alpha-gal IgE; Non-celiac gluten sensitivity; Alpha-gal; Lone star tick; Food exposure allergy |
| Core Tip |
Integrating alpha-gal syndrome into the differential diagnosis of unexplained postprandial gastrointestinal symptoms - particularly in individuals from or with travel to tick-endemic areas - is imperative. Awareness of the unique etiologic and immunologic underpinnings of alpha-gal syndrome provides clinicians with a framework to recognize atypical presentations. Concerted efforts are needed to refine diagnostic algorithms, including the judicious use of serum α-gal-specific IgE testing in appropriate clinical contexts, and to develop multidisciplinary pathways linking gastroenterology, allergy/immunology and nutrition. |
| Publish Date |
2026-01-16 11:31 |
| Citation |
Awosika A, Balaji P. Misdiagnosis of alpha-gal syndrome as non-celiac gluten sensitivity or lactose intolerance: A diagnostic blind spot for clinicians. World J Gastroenterol 2026; 32(3): 116350
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i3/116350.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i3.116350 |
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