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4/3/2026 6:41:52 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 116380
Country Greece
Received
2025-11-10 05:38
Peer-Review Started
2025-11-10 05:44
First Decision by Editorial Office Director
2025-12-30 07:30
Return for Revision
2025-12-30 07:30
Revised
2025-12-30 17:10
Publication Fee Transferred
Second Decision by Editor
2026-01-21 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-21 08:37
Articles in Press
2026-01-21 08:37
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 08:02
Publish the Manuscript Online
2026-04-03 06:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Correspondence
Article Title Letter to the Editor: Does hepatectomy outweigh radiofrequency ablation in the management of small hepatocellular carcinoma?
Manuscript Source Invited Manuscript
All Author List Dimitrios S Karagiannakis
ORCID
Author(s) ORCID Number
Dimitrios S Karagiannakis http://orcid.org/0000-0003-0082-634X
Funding Agency and Grant Number
Corresponding Author Dimitrios S Karagiannakis, Assistant Professor, Fourth Department of Internal Medicine, Academic Hospital “Attikon”, Medical School of the National and Kapodistrian University of Athens, Aghiou Thoma 17, Athens 12462, Greece. dkarag@med.uoa.gr
Key Words Hepatocellular carcinoma; Early stage; Radiofrequency ablation; Surgical resection; Hepatectomy; Survival; Outcomes; Postoperative complications
Core Tip The optimal treatment of patients with liver cirrhosis and early hepatocellular carcinomas who are not suitable candidates for liver transplantation is still a matter of debate. Percutaneous ablation has shown effectiveness for liver tumors smaller than 3 cm, and it typically results in fewer postoperative complications compared to surgical resection. However, surgical resection appears to provide better long-term outcomes, including higher rates of recurrence-free survival and overall survival. Consequently, it should be the preferred approach in tumors larger than 3 cm or those located in areas where satisfactory peritumoral margins cannot be achieved, making it challenging to secure an extended and effective ablation.
Publish Date 2026-04-03 06:41
Citation

Karagiannakis DS. Letter to the Editor: Does hepatectomy outweigh radiofrequency ablation in the management of small hepatocellular carcinoma? World J Gastroenterol 2026; 32(14): 116380

URL https://www.wjgnet.com/1007-9327/full/v32/i14/116380.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i14.116380
Manuscript File 116380_Auto_Edited_064547.docx
Answering Reviewers 116380-answering-reviewers.pdf
Audio Core Tip 116380-audio.m4a
Conflict-of-Interest Disclosure Form 116380-conflict-of-interest-statement.pdf
Copyright License Agreement 116380-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116380-non-native-speakers.pdf
Peer-review Report 116380-peer-reviews.pdf
Scientific Misconduct Check 116380-scientific-misconduct-check.png
Scientific Editor Work List 116380-scientific-editor-work-list.pdf
CrossCheck Report 116380-crosscheck-report.pdf