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Publication Name World Journal of Clinical Oncology
Manuscript ID 116390
Country China
Received
2025-11-11 11:52
Peer-Review Started
2025-11-12 00:23
First Decision by Editorial Office Director
2025-11-24 12:38
Return for Revision
2025-11-24 12:38
Revised
2025-12-01 16:59
Publication Fee Transferred
Second Decision by Editor
2025-12-24 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-24 10:44
Articles in Press
2025-12-24 10:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-29 10:16
Publish the Manuscript Online
2026-02-06 06:30
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Editorial
Article Title Role of claudin-6 in high-grade endometrial carcinoma: Implications for risk stratification and personalized treatment strategies
Manuscript Source Invited Manuscript
All Author List Chuang Cai, Jin-Man Chen, Zu-Xun Qiu and Shu-Qi Ren
ORCID
Author(s) ORCID Number
Chuang Cai http://orcid.org/0000-0002-9660-0160
Jin-Man Chen http://orcid.org/0000-0002-5672-373X
Shu-Qi Ren http://orcid.org/0009-0004-9589-199X
Funding Agency and Grant Number
Funding Agency Grant Number
Zhongshan Science and Technology Bureau 2023B1033
Corresponding Author Shu-Qi Ren, Associate Research Scientist, Department of Laboratory Medicine, Zhongshan Integrated Traditional Chinese and Western Medicine Hospital, No. 10 Dexiu Road, Zhongshan 528467, Guangdong Province, China. shuchijen@163.com
Key Words Claudin-6; High-grade endometrial carcinoma; Risk stratification; Therapeutic target; Prognosis
Core Tip This editorial focuses on the expression and clinical importance of the tight junction protein claudin-6 (CLDN6) in high-grade endometrial carcinoma. It demonstrates that CLDN6 overexpression independently correlates with aggressive pathological characteristics and poor patient outcomes. These findings underscore CLDN6’s value as a prognostic biomarker and highlight its potential as a therapeutic target, opening new possibilities for improved risk stratification and personalized treatment strategies in high-grade endometrial carcinoma.
Publish Date 2026-02-06 06:30
Citation

Cai C, Chen JM, Qiu ZX, Ren SQ. Role of claudin-6 in high-grade endometrial carcinoma: Implications for risk stratification and personalized treatment strategies. World J Clin Oncol 2026; 17(2): 116390

URL https://www.wjgnet.com/2218-4333/full/v17/i2/116390.htm
DOI https://dx.doi.org/10.5306/wjco.v17.i2.116390
Full Article (PDF) WJCO-17-116390-with-cover.pdf
Manuscript File 116390_Auto_Edited_114505.docx
Answering Reviewers 116390-answering-reviewers.pdf
Audio Core Tip 116390-audio.mp3
Conflict-of-Interest Disclosure Form 116390-conflict-of-interest-statement.pdf
Copyright License Agreement 116390-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116390-non-native-speakers.pdf
Peer-review Report 116390-peer-reviews.pdf
Scientific Misconduct Check 116390-scientific-misconduct-check.png
Scientific Editor Work List 116390-scientific-editor-work-list.pdf
CrossCheck Report 116390-crosscheck-report.pdf