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4/17/2026 7:16:57 AM | Browse: 4 | Download: 11
Publication Name World Journal of Gastroenterology
Manuscript ID 116405
Country China
Received
2025-11-11 12:24
Peer-Review Started
2025-11-11 12:24
First Decision by Editorial Office Director
2026-01-08 09:24
Return for Revision
2026-01-08 09:24
Revised
2026-01-20 11:55
Publication Fee Transferred
2026-01-22 14:11
Second Decision by Editor
2026-02-10 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-10 08:51
Articles in Press
2026-02-10 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-07 03:24
Publish the Manuscript Online
2026-04-17 07:16
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort
Manuscript Source Unsolicited Manuscript
All Author List Han-Shuo Wang, Yu-Xin Lin, Si-Rui Xu, Li-Ya Wang, Xiao-Dong Wang and Ming-Jun Huang
ORCID
Author(s) ORCID Number
Han-Shuo Wang http://orcid.org/0009-0002-4877-5094
Xiao-Dong Wang http://orcid.org/0000-0002-5617-3627
Ming-Jun Huang http://orcid.org/0000-0002-4623-0114
Funding Agency and Grant Number
Funding Agency Grant Number
Clinical Research Incubation Project of West China Hospital of Sichuan University 2021HXFH052
1·3·5 Projects for Artificial Intelligence of West China Hospital of Sichuan University ZYAI24067
Corresponding Author Xiao-Dong Wang, MD, PhD, Professor, Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. wangxiaodong@wchscu.cn
Key Words Rectal cancer; Low anterior resection syndrome; Tumor location; Propensity score matching; Longitudinal studies
Core Tip Parallel recovery trajectory: After propensity score matching, the ultra-low and non-ultra-low rectal cancer groups shared a similar rate of functional improvement throughout the first postoperative year. Persistently higher risk: Despite the similar recovery pace, the ultra-low group consistently faced a significantly higher overall risk of low anterior resection syndrome (LARS), attributable to a worse initial functional baseline. Clinical implication: These findings establish tumor height as a critical, independent determinant of LARS, underscoring the need for tailored counseling and proactive management strategies for patients with ultra-low tumors.
Publish Date 2026-04-17 07:16
Citation

Wang HS, Lin YX, Xu SR, Wang LY, Wang XD, Huang MJ. Longitudinal evolution of low anterior resection syndrome in ultra-low rectal cancer: A trend analysis of a propensity-matched cohort. World J Gastroenterol 2026; 32(16): 116405

URL https://www.wjgnet.com/1007-9327/full/v32/i16/116405.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i16.116405
Full Article (PDF) WJG-32-116405-with-cover.pdf
STROBE Statement 116405-STROBE-statement.pdf
Manuscript File 116405_Auto_Edited_072341.docx
Answering Reviewers 116405-answering-reviewers.pdf
Audio Core Tip 116405-audio.mp3
Biostatistics Review Certificate 116405-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116405-conflict-of-interest-statement.pdf
Copyright License Agreement 116405-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116405-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116405-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116405-non-native-speakers.pdf
Supplementary Material 116405-supplementary-material.pdf
Peer-review Report 116405-peer-reviews.pdf
Scientific Misconduct Check 116405-scientific-misconduct-check.png
Scientific Editor Work List 116405-scientific-editor-work-list.pdf
CrossCheck Report 116405-crosscheck-report.pdf