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Articles Published Processes
5/28/2026 8:52:28 AM | Browse: 0 | Download: 0
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Received |
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2025-11-11 12:00 |
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Peer-Review Started |
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2025-11-11 12:01 |
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First Decision by Editorial Office Director |
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2025-12-30 05:39 |
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Return for Revision |
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2025-12-30 05:39 |
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Revised |
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2026-01-05 15:28 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-10 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-10 04:44 |
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Articles in Press |
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2026-02-10 04:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-29 03:29 |
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Publish the Manuscript Online |
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2026-05-28 08:52 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
Beyond vision: The overlooked burden of depression in glaucoma patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Matteo Capobianco, Francesco Cappellani, Marieme Khouyyi, Simonetta Gaia Nicolosi, Fabiana D’Esposito, Mutali Musa, Marco Battista, Piero Barboni, Caterina Gagliano and Marco Zeppieri |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, Consultant, MD, PhD, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Glaucoma; Quality of life; Depression; Neurodegeneration; Eye-brain axis; Retinal ganglion cells; Circadian dysfunction; Mental health assessment |
| Core Tip |
Depression is common in people with glaucoma and still too often missed. The slow loss of vision, the fear of blindness, reduced social participation, and the day-to-day burden of complex treatment plans all take a psychological toll and erode quality of life. When depressive symptoms are present, patients are less likely to adhere to medications, sustain self-care, or keep follow-up appointments - behaviors that, in turn, can worsen visual outcomes. Emerging evidence also points to shared biology between glaucoma and depression. Neuroinflammation, mitochondrial dysfunction, and dysregulation of the hypothalamic-pituitary-adrenal axis recurs across both conditions and may help explain their clinical co-occurrence. For these reasons, routine identification and management of depression should be part of glaucoma care: Addressing mental health is not ancillary - it is integral to protecting vision. |
| Publish Date |
2026-05-28 08:52 |
| Citation |
Capobianco M, Cappellani F, Khouyyi M, Nicolosi SG, D’Esposito F, Musa M, Battista M, Barboni P, Gagliano C, Zeppieri M. Beyond vision: The overlooked burden of depression in glaucoma patients. World J Psychiatry 2026; 16(6): 116408 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i6/116408.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i6.116408 |
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