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4/3/2026 6:41:51 AM | Browse: 2 | Download: 3
Publication Name World Journal of Gastroenterology
Manuscript ID 116415
Country China
Received
2025-11-17 12:13
Peer-Review Started
2025-11-18 03:03
First Decision by Editorial Office Director
2025-12-11 10:11
Return for Revision
2025-12-11 10:11
Revised
2025-12-23 08:28
Publication Fee Transferred
2025-12-26 14:41
Second Decision by Editor
2026-02-03 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 04:22
Articles in Press
2026-02-03 04:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-27 02:21
Publish the Manuscript Online
2026-04-03 06:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Retrospective Study
Article Title Development and validation of prognostic models for colon cancer incorporating extramural vascular invasion assessed by contrast-enhanced computed tomography
Manuscript Source Unsolicited Manuscript
All Author List Mei-Rong Wang, Liang-Fang Zheng, Fan Yang, Xiao-Yu Gu, Ju-Shun Yang, Fei-Xiang Chen, Jia-Min Liu and Bo-Sheng He
ORCID
Author(s) ORCID Number
Mei-Rong Wang http://orcid.org/0000-0002-1302-7996
Fei-Xiang Chen http://orcid.org/0000-0001-8227-1960
Bo-Sheng He http://orcid.org/0000-0002-2242-2031
Funding Agency and Grant Number
Funding Agency Grant Number
Nantong University Special Research Fund for Clinical Medicine No. 2024LQ022
Jiangsu Commission of Health No. ZD2021059
Nantong Municipal Commission of Health and Family Planning No. QA2020002
Corresponding Author Bo-Sheng He, PhD, Department of Radiology, Nantong First People’s Hospital, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. boshenghe@126.com
Key Words Colon cancer; Computed tomography-detected extramural vascular invasion; Disease-free survival; Machine learning; Nomogram
Core Tip Extramural vascular invasion represents a well-established determinant of prognosis in colon cancer; however, its reliable evaluation before surgery remains clinically challenging. The present study provided evidence that computed tomography-detected extramural vascular invasion (ctEMVI) functioned as an independent predictor of disease-free survival following curative resection. By incorporating ctEMVI with conventional clinicopathological factors, we developed interpretable machine-learning-based prediction models and a nomogram to enhance individualized preoperative risk assessment. Among the evaluated algorithms, CoxBoost demonstrated the strongest predictive capability. Collectively, these results underscored the clinical utility of ctEMVI-driven modeling approaches for refining preoperative risk stratification in patients with colon cancer.
Publish Date 2026-04-03 06:41
Citation

Wang MR, Zheng LF, Yang F, Gu XY, Yang JS, Chen FX, Liu JM, He BS. Development and validation of prognostic models for colon cancer incorporating extramural vascular invasion assessed by contrast-enhanced computed tomography. World J Gastroenterol 2026; 32(14): 116415

URL https://www.wjgnet.com/1007-9327/full/v32/i14/116415.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i14.116415
Full Article (PDF) WJG-32-116415-with-cover.pdf
Manuscript File 116415_Auto_Edited_070935.docx
Answering Reviewers 116415-answering-reviewers.pdf
Audio Core Tip 116415-audio.m4a
Biostatistics Review Certificate 116415-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116415-conflict-of-interest-statement.pdf
Copyright License Agreement 116415-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116415-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116415-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116415-non-native-speakers.pdf
Supplementary Material 116415-supplementary-material.pdf
Peer-review Report 116415-peer-reviews.pdf
Scientific Misconduct Check 116415-scientific-misconduct-check.png
Scientific Editor Work List 116415-scientific-editor-work-list.pdf
CrossCheck Report 116415-crosscheck-report.pdf