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Articles Published Processes
2/6/2026 8:53:11 AM | Browse: 0 | Download: 0
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Received |
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2025-11-11 12:03 |
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Peer-Review Started |
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2025-11-11 12:03 |
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First Decision by Editorial Office Director |
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2025-11-30 02:16 |
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Return for Revision |
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2025-11-30 02:16 |
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Revised |
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2025-12-11 02:37 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-25 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-25 09:50 |
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Articles in Press |
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2025-12-25 09:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-29 01:17 |
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Publish the Manuscript Online |
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2026-02-06 08:53 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Beyond monotherapy by acid suppression: Reshaping the management of refractory gastroesophageal reflux disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xin-Ye Zuo and Qian-Qian Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| General Program of Municipal Natural Science Foundation of Beijing |
7232151 |
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| Corresponding Author |
Qian-Qian Chen, Professor, Department of Gastroenterology and Hepatology, The First Medical Center of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. qian_qian_chen@163.com |
| Key Words |
Refractory gastroesophageal reflux disease; Anxiety; Holistic medicine; Endoscopic intervention; Multidisciplinary management |
| Core Tip |
A recent Shanghai study identified prolonged disease duration and anxiety as key risk factors for refractory gastroesophageal reflux disease, whereas moderate physical activity is protective. Management should extend beyond standard acid suppression to include a “multidimensional” strategy incorporating anti-anxiety interventions, exercise prescriptions, and multidisciplinary collaboration. However, the study’s single-region sample and cross-sectional design necessitate future multi-regional, long-term research to validate and establish causality. |
| Publish Date |
2026-02-06 08:53 |
| Citation |
Zuo XY, Chen QQ. Beyond monotherapy by acid suppression: Reshaping the management of refractory gastroesophageal reflux disease. World J Gastroenterol 2026; 32(7): 116425 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i7/116425.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i7.116425 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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