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5/28/2026 8:52:22 AM | Browse: 2 | Download: 4
Publication Name World Journal of Psychiatry
Manuscript ID 116435
Country China
Received
2025-11-12 08:05
Peer-Review Started
2025-11-12 08:05
First Decision by Editorial Office Director
2025-12-23 09:59
Return for Revision
2025-12-23 09:59
Revised
2026-01-06 05:11
Publication Fee Transferred
2026-01-19 06:12
Second Decision by Editor
2026-02-28 02:28
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-28 02:43
Articles in Press
2026-02-28 02:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-07 10:31
Publish the Manuscript Online
2026-05-28 08:52
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Observational Study
Article Title Thyroid-stimulating hormone levels and suicide attempts in Chinese patients with first-episode drug-naïve major depressive disorder
Manuscript Source Unsolicited Manuscript
All Author List Han-Xu Deng, Yao-Zhi Liu, Lin Yang, Jun-Jun Liu, Feng-Nan Jia, Xue-Li Zhao, Xing-Zhi Xia, Xiang-Yang Zhang and Xiang-Dong Du
ORCID
Author(s) ORCID Number
Han-Xu Deng http://orcid.org/0009-0002-6762-0418
Xiang-Dong Du http://orcid.org/0009-0007-5205-0033
Funding Agency and Grant Number
Funding Agency Grant Number
Medical research key project of Jiangsu Provincial Health Commission No. K2023015
Suzhou Major Diseases Clinical Multi-Center Research Project No. DZXYJ202414
Scientific and Technological Key Program of Suzhou No. SYW2024008
Key Discipline of Psychiatry in Suzhou No. SZXK202521
Corresponding Author Xiang-Dong Du, Chief Physician, Professor, Department of Psychiatry, Suzhou Guangji Hospital, The Affiliated Guangji Hospital of Soochow University, No. 11 Guangqian Road, Suzhou 215004, Jiangsu Province, China. xiangdong-du@163.com
Key Words Thyroid-stimulating hormone; Suicide attempts; Thyroid dysfunction; First-episode drug naïve; Major depressive disorder; Non-linear relationship
Core Tip This study investigates the relationship between thyroid-stimulating hormone (TSH) levels and suicide attempts in first-episode drug-naïve major depressive disorder patients. The results show a positive independent correlation between TSH levels and suicide attempts, with a significant increase in the correlation when TSH exceeds 5.43 µIU/mL. This finding provides a new biomarker-based perspective for early suicide risk identification in depressed patients.
Publish Date 2026-05-28 08:52
Citation

Deng HX, Liu YZ, Yang L, Liu JJ, Jia FN, Zhao XL, Xia XZ, Zhang XY, Du XD. Thyroid-stimulating hormone levels and suicide attempts in Chinese patients with first-episode drug-naïve major depressive disorder. World J Psychiatry 2026; 16(6): 116435

URL https://www.wjgnet.com/2220-3206/full/v16/i6/116435.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i6.116435
Full Article (PDF) WJP-16-116435-with-cover.pdf
STROBE Statement 116435-STROBE-statement.pdf
Manuscript File 116435_Auto_Edited-WJJ.docx
Answering Reviewers 116435-answering-reviewers.pdf
Audio Core Tip 116435-audio.m4a
Biostatistics Review Certificate 116435-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116435-conflict-of-interest-statement.pdf
Copyright License Agreement 116435-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116435-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116435-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116435-non-native-speakers.pdf
Supplementary Material 116435-supplementary-material.pdf
Peer-review Report 116435-peer-reviews.pdf
Scientific Misconduct Check 116435-scientific-misconduct-check.png
Scientific Editor Work List 116435-scientific-editor-work-list.pdf
CrossCheck Report 116435-crosscheck-report.pdf