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Articles Published Processes
12/13/2014 7:02:00 PM | Browse: 1321 | Download: 1811
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Received |
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2014-05-29 09:29 |
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Peer-Review Started |
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2014-05-29 21:40 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2014-07-30 10:57 |
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Revised |
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2014-08-16 05:43 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2014-09-10 13:29 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2014-09-10 13:53 |
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Articles in Press |
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2014-09-10 13:53 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-14 16:26 |
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Publish the Manuscript Online |
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2014-12-13 19:01 |
| Category |
Cell Biology |
| Manuscript Type |
Topic Highlights |
| Article Title |
B7-H4 as a protective shield for pancreatic islet beta cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Annika C Sun, Dawei Ou, Dan S Luciani and Garth L Warnock |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| CIHR |
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| JDRF |
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| UBC Hospital Foundation |
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| Corresponding Author |
Garth L Warnock, MSc, MD, Department of Surgery, Vancouver General Hospital, University of British Columbia, 3109-910 West 10th Ave, Vancouver BC V5Z 4E3, Canada. garth.warnock@vch.ca
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| Key Words |
Diabetes mellitus; Autoimmunity; Transplantation; Co-stimulation blockade; Biomarker |
| Core Tip |
Onset of type 1 diabetes is driven by defects in immune regulation, resulting in β-cell autoimmunity. However, there may be mechanisms inherent to the β-cell that may prevent or slow development of autoimmunity and progression of disease. One such factor is B7-H4, which acts at the islet-immune interface to defend β-cells from autoimmune diabetes and to protect transplanted islet allografts.
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| Publish Date |
2014-12-13 19:01 |
| Citation |
Sun AC, Ou D, Luciani DS, Warnock GL. B7-H4 as a protective shield for pancreatic islet beta cells. World J Diabetes 2014; 5(6): 739-746 |
| URL |
http://www.wjgnet.com/1948-9358/full/v5/i6/739.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v5.i6.739 |
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