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9/2/2026 6:35:30 AM | Browse: 1 | Download: 2
Publication Name Artificial Intelligence in Cancer
Manuscript ID 116464
Country China
Received
2025-11-12 02:39
Peer-Review Started
2025-11-12 02:39
First Decision by Editorial Office Director
2025-12-02 08:09
Return for Revision
2025-12-02 08:09
Revised
2025-12-04 17:20
Publication Fee Transferred
Second Decision by Editor
2026-02-02 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-02 07:18
Articles in Press
2026-02-02 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-13 02:01
Publish the Manuscript Online
2026-09-02 06:35
ISSN 2644-3228 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Retrospective Cohort Study
Article Title Prognostic value of early changes in artificial intelligence-based computed tomography-measured body composition in pediatric osteosarcoma receiving neoadjuvant chemotherapy
Manuscript Source Invited Manuscript
All Author List Yu-Han Yang and Yuan Li
ORCID
Author(s) ORCID Number
Yu-Han Yang http://orcid.org/0000-0002-4405-5711
Yuan Li http://orcid.org/0009-0008-6350-4632
Funding Agency and Grant Number
Corresponding Author Yuan Li, MD, Professor, State Key Laboratory of Biotherapy and Cancer Center, Department of Pediatric Surgery, Laboratory of Digestive Surgery, West China Hospital, Sichuan University, a, Chengdu 6100000, Sichuan Province, China. l13258389785@126.com
Key Words Overall survival; Artificial intelligence; Body composition; Pediatrics; Osteosarcoma
Core Tip Using artificial intelligence based automated computed tomography analysis of the third lumbar vertebra body composition in 133 pediatric osteosarcoma patients, early reductions in skeletal muscle density during neoadjuvant chemotherapy were independently associated with poor histologic response and shorter overall survival. An integrated index combining age, post chemotherapy inflammatory indicator and change of skeletal muscle density improved prediction of treatment response and prognosis, suggesting that early computed tomography-derived muscle metrics can guide timely nutritional and rehabilitative interventions to potentially improve outcomes.
Publish Date 2026-09-02 06:35
Citation

Yang YH, Li Y. Prognostic value of early changes in artificial intelligence-based computed tomography-measured body composition in pediatric osteosarcoma receiving neoadjuvant chemotherapy. Artif Intell Cancer 2026; 7(1): 116464

URL https://www.wjgnet.com/2644-3228/full/v7/i1/116464.htm
DOI https://doi.org/10.35713/aic.v7.i1.116464
Full Article (PDF) AIC-7-116464-with-cover.pdf
STROBE Statement 116464-STROBE-statement.pdf
Manuscript File 116464_Auto_Edited_081158.docx
Answering Reviewers 116464-answering-reviewers.pdf
Audio Core Tip 116464-audio.mp3
Biostatistics Review Certificate 116464-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 116464-conflict-of-interest-statement.pdf
Copyright License Agreement 116464-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 116464-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 116464-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 116464-non-native-speakers.pdf
Peer-review Report 116464-peer-reviews.pdf
Scientific Misconduct Check 116464-scientific-misconduct-check.png
CrossCheck Report 116464-crosscheck-report.pdf