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3/27/2026 6:07:05 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 116481
Country Chile
Received
2025-11-13 04:48
Peer-Review Started
2025-11-13 04:49
First Decision by Editorial Office Director
2025-12-12 09:26
Return for Revision
2025-12-12 09:26
Revised
2025-12-18 21:00
Publication Fee Transferred
Second Decision by Editor
2026-01-19 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-19 07:28
Articles in Press
2026-01-19 07:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 08:03
Publish the Manuscript Online
2026-03-27 06:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Correspondence
Article Title AADN score predicts overall and progression-free survival in triple therapy for hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Cristian Lindner
ORCID
Author(s) ORCID Number
Cristian Lindner http://orcid.org/0000-0002-2642-4288
Funding Agency and Grant Number
Corresponding Author Cristian Lindner, Department of Radiology, Faculty of Medicine, University of Concepción, San Martín 1436, Concepción 4030000, Chile. clindner146@gmail.com
Key Words Hepatocellular carcinoma; Oncology; Interventional radiology; Overall survival; Liver cancer
Core Tip The AADN score, derived from alpha-fetoprotein, alkaline phosphatase, direct bilirubin, and neutrophil-to-lymphocyte ratio, provides a simple yet powerful tool to predict overall and progression-free survival in patients with unresectable hepatocellular carcinoma treated with transarterial chemoembolization, sintilimab, and lenvatinib. By integrating markers of tumor biology, hepatic function, and systemic inflammation, this model enables individualized risk stratification and supports precision-based decision-making in triple therapy for hepatocellular carcinoma.
Publish Date 2026-03-27 06:07
Citation

Lindner C. AADN score predicts overall and progression-free survival in triple therapy for hepatocellular carcinoma. World J Gastroenterol 2026; 32(13): 116481

URL https://www.wjgnet.com/1007-9327/full/v32/i13/116481.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i13.116481
Full Article (PDF) WJG-32-116481-with-cover.pdf
Manuscript File 116481_Auto_Edited_074753.docx
Answering Reviewers 116481-answering-reviewers.pdf
Audio Core Tip 116481-audio.ogg
Conflict-of-Interest Disclosure Form 116481-conflict-of-interest-statement.pdf
Copyright License Agreement 116481-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116481-non-native-speakers.pdf
Peer-review Report 116481-peer-reviews.pdf
Scientific Misconduct Check 116481-scientific-misconduct-check.png
Scientific Editor Work List 116481-scientific-editor-work-list.pdf
CrossCheck Report 116481-crosscheck-report.pdf