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Articles Published Processes
12/1/2014 2:43:00 PM | Browse: 1186 | Download: 1339
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Received |
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2014-05-29 08:44 |
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Peer-Review Started |
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2014-05-29 20:36 |
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To Make the First Decision |
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2014-07-10 17:23 |
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Return for Revision |
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2014-07-11 15:34 |
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Revised |
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2014-07-29 09:46 |
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Second Decision |
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2014-09-10 09:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-10 09:30 |
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Articles in Press |
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2014-09-10 09:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-20 15:38 |
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Publish the Manuscript Online |
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2014-12-01 14:43 |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Topic Highlights |
Article Title |
Importance of genetic evaluation and testing in pediatric cardiomyopathy
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Manuscript Source |
Invited Manuscript |
All Author List |
Muhammad Tariq and Stephanie M Ware |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Children’s Cardiomyopathy Foundation |
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Cincinnati Children’s Hospital’s Clinical and Translational Science Award |
NIH-ULlRR026314 (to Ware SM) |
AHA Postdoctoral Fellowship Award |
12POST10370002 (to Tariq M) |
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Corresponding Author |
Stephanie M Ware, MD, PhD, Department of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut Street Indianapolis, IN 46202, United States. stware@iu.edu
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Key Words |
Pediatric; Mutation; Exome sequencing; Sarcomere |
Core Tip |
Pediatric cardiomyopathy is a clinically and genetically heterogeneous heart muscle disease with five major phenotypes: hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, left ventricular noncompaction cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy. The genetic basis of these cardiomyopathies has been identified using traditional linkage analysis and sequencing. Novel gene discovery has been increased using modern next generation sequencing technologies, however the exact mechanisms of disease development are not fully known. In this review we focus on the current genetic knowledge of cardiomyopathies and their importance in diagnostic settings.
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Publish Date |
2014-12-01 14:43 |
Citation |
Tariq M, Ware SM. Importance of genetic evaluation and testing in pediatric cardiomyopathy. World J Cardiol 2014; 6(11): 1156-1165 |
URL |
http://www.wjgnet.com/1949-8462/full/v6/i11/1156.htm |
DOI |
http://dx.doi.org/10.4330/wjc.v6.i11.1156 |
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