BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/30/2026 1:40:20 PM | Browse: 2 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 116530
Country China
Received
2025-11-14 04:02
Peer-Review Started
2025-11-14 04:03
First Decision by Editorial Office Director
2025-12-25 08:45
Return for Revision
2025-12-25 08:45
Revised
2026-01-07 14:11
Publication Fee Transferred
Second Decision by Editor
2026-01-26 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-26 09:07
Articles in Press
2026-01-26 09:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-26 05:48
Publish the Manuscript Online
2026-06-30 13:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication: Clinical, pharmacogenetic, and microbiome perspectives
Manuscript Source Invited Manuscript
All Author List Hou-Shu Tu, Meng-Lin Chen, Jing Hong and Ling He
ORCID
Author(s) ORCID Number
Hou-Shu Tu http://orcid.org/0009-0007-2810-1080
Ling He http://orcid.org/0000-0002-5198-712X
Funding Agency and Grant Number
Corresponding Author Ling He, Chief Physician, PhD, Professor, Department of Gastroenterology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, No. 445 Bayi Avenue, Nanchang 330006, Jiangxi Province, China. heling118@126.com
Key Words Helicobacter pylori; Vonoprazan-amoxicillin dual therapy; First-line eradication; Antibiotic resistance; Pharmacogenetics; Gut microbiome; Treatment optimization; Antimicrobial stewardship
Core Tip Vonoprazan-amoxicillin dual therapy is a potent, well-tolerated first-line regimen for Helicobacter pylori eradication, even in regions with clarithromycin resistance. This opinion review integrates multicenter evidence, pharmacogenetics, and microbiome considerations, highlights unresolved controversies, and proposes a sequential roadmap for safe, globally applicable implementation and reduce the global burden of associated gastrointestinal disease.
Publish Date 2026-06-30 13:40
Citation

Tu HS, Chen ML, Hong J, He L. Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication: Clinical, pharmacogenetic, and microbiome perspectives. World J Gastroenterol 2026; 32(26): 116530

URL https://www.wjgnet.com/1007-9327/full/v32/i26/116530.htm
DOI https://doi.org/10.3748/wjg.116530
Full Article (PDF) WJG-32-116530-with-cover.pdf
Manuscript File 116530_Auto_Edited_060131.docx
Answering Reviewers 116530-answering-reviewers.pdf
Audio Core Tip 116530-audio.mp3
Conflict-of-Interest Disclosure Form 116530-conflict-of-interest-statement.pdf
Copyright License Agreement 116530-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116530-non-native-speakers.pdf
Peer-review Report 116530-peer-reviews.pdf
Scientific Misconduct Check 116530-scientific-misconduct-check.png
Scientific Editor Work List 116530-scientific-editor-work-list.pdf
CrossCheck Report 116530-crosscheck-report.pdf