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Articles Published Processes
5/26/2026 3:52:11 AM | Browse: 1 | Download: 0
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Received |
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2025-11-17 03:48 |
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Peer-Review Started |
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2025-11-17 07:24 |
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First Decision by Editorial Office Director |
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2026-01-08 09:25 |
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Return for Revision |
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2026-01-09 07:51 |
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Revised |
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2026-01-18 08:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-12 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-12 08:24 |
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Articles in Press |
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2026-03-12 08:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-14 08:16 |
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Publish the Manuscript Online |
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2026-05-26 03:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Liver injury after COVID-19 vaccination: Current status and future perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ken Sato |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ken Sato, MD, PhD, Professor, Department of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaorui-machi, Takasaki 370-0033, Japan. satoken@gunma-u.ac.jp |
| Key Words |
SARS-CoV-2; COVID-19; Vaccination; Liver injury; Autoimmunity |
| Core Tip |
Liver injury following coronavirus disease 2019 vaccination presents with heterogeneous phenotypes, including new-onset autoimmune hepatitis, drug-induced autoimmune-like hepatitis, drug-induced liver injury, and secondary hepatic manifestations linked to comorbidities such as hemophagocytic lymphohistiocytosis. Vaccine-type differences in liver injury remain inconclusive. Prognosis varies by etiology; although many cases resolve spontaneously or respond to immunosuppressive therapy, some progress to acute liver failure necessitating transplantation or resulting in death. Vaccine rechallenge may not be contraindicated, but switching vaccine platforms is advised. The pathogenesis likely involves multifactorial mechanisms, such as genetic predispositions and immunological cross-reactivity between viral-specific antigens and host self-proteins. |
| Publish Date |
2026-05-26 03:52 |
| Citation |
Sato K. Liver injury after COVID-19 vaccination: Current status and future perspectives. World J Hepatol 2026; 18(5): 116542 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i5/116542.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i5.116542 |
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