BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/7/2026 9:40:27 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 116559
Country China
Received
2025-11-14 10:15
Peer-Review Started
2025-11-14 10:15
First Decision by Editorial Office Director
2026-01-09 07:49
Return for Revision
2026-01-09 07:49
Revised
2026-01-15 13:03
Publication Fee Transferred
Second Decision by Editor
2026-02-14 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-14 08:11
Articles in Press
2026-02-14 08:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-08 07:06
Publish the Manuscript Online
2026-08-07 09:40
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Correspondence
Article Title Letter to the Editor: Total neoadjuvant therapy for locally advanced rectal cancer: Navigating beyond surgical outcomes to holistic patient-centered care
Manuscript Source Unsolicited Manuscript
All Author List Shi-Qiong Zhou and Qing-Hua Ke
ORCID
Author(s) ORCID Number
Shi-Qiong Zhou http://orcid.org/0009-0000-5619-2978
Qing-Hua Ke http://orcid.org/0009-0003-3582-3824
Funding Agency and Grant Number
Corresponding Author Qing-Hua Ke, Chief Physician, PhD, Department of Chemoradiotherapy, Jingzhou No. 1 People’s Hospital and First Affiliated Hospital of Yangtze University, No. 10 Tianhu Road, Shashi District, Jingzhou 434000, Hubei Province, China. 3803354759@qq.com
Key Words Locally advanced rectal cancer; Total neoadjuvant therapy; Surgical outcomes; Functional preservation; Patient-centered care; Minimally invasive surgery; Biomarker stratification; Long-term survival
Core Tip Locally advanced rectal cancer treatment is evolving from surgery-centric to multimodal strategies, with total neoadjuvant therapy (TNT) gaining attention for balancing curability and function. Jabbar et al’s study confirms that TNT-RAPIDO is surgically safe, achieving comparable R0 resection rates to standard chemoradiotherapy while reducing stoma duration and permanent stoma risk. We highlight the study’s contributions to resolving TNT-related uncertainties and propose future directions: (1) Validating findings in multicenter cohorts; (2) Evaluating long-term oncologic outcomes; (3) Integrating patient-reported measures; and (4) Developing personalized regimens. This shift toward holistic care ensures locally advanced rectal cancer treatment prioritizes both survival and quality of life.
Publish Date 2026-08-07 09:40
Citation

Zhou SQ, Ke QH. Letter to the Editor: Total neoadjuvant therapy for locally advanced rectal cancer: Navigating beyond surgical outcomes to holistic patient-centered care. World J Gastrointest Oncol 2026; 18(8): 116559

URL https://www.wjgnet.com/1948-5204/full/v18/i8/116559.htm
DOI https://doi.org/10.4251/wjgo.116559
Full Article (PDF) WJGO-18-116559-with-cover.pdf
Manuscript File 116559_Auto_Edited_032652.docx
Answering Reviewers 116559-answering-reviewers.pdf
Audio Core Tip 116559-audio.wav
Conflict-of-Interest Disclosure Form 116559-conflict-of-interest-statement.pdf
Copyright License Agreement 116559-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116559-non-native-speakers.pdf
Peer-review Report 116559-peer-reviews.pdf
Scientific Misconduct Check 116559-scientific-misconduct-check.png
Scientific Editor Work List 116559-scientific-editor-work-list.pdf
CrossCheck Report 116559-crosscheck-report.pdf